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Target
Interleukin-17F
Ligand
BDBM247028
Substrate
n/a
IC50
<10000±n/a nM
Citation
 Gaweco, A; Tilley, J; Blinn, J Sulfonamide retinoic acid receptor-related orphan receptor modulators and uses thereof US Patent  US9701663 Publication Date 7/11/2017 
Target
Name:
Interleukin-17F
Synonyms:
Cytokine ML-1 | IL17F | IL17F_HUMAN | il-17f
Type:
Enzyme Catalytic Domain
Mol. Mass.:
18053.35
Organism:
Homo sapiens (Human)
Description:
Q96PD4
Residue:
163
Sequence:
MTVKTLHGPAMVKYLLLSILGLAFLSEAAARKIPKVGHTFFQKPESCPPVPGGSMKLDIGIINENQRVSMSRNIESRSTSPWNYTVTWDPNRYPSEVVQAQCRNLGCINAQGKEDISMNSVPIQQETLVVRRKHQGCSVSFQLEKVLVTVGCTCVTPVIHHVQ
  
Inhibitor
Name:
BDBM247028
Synonyms:
1-((5,5-dimethyl-1-(phenylsulfonyl)pyrrolidin-3-yl)methyl)-5-(1H-pyrazol-4-yl)-1H-indole | US9701663, 29
Type:
Small organic molecule
Emp. Form.:
C24H26N4O2S
Mol. Mass.:
434.554
SMILES:
CC1(C)CC(Cn2ccc3cc(ccc23)-c2cn[nH]c2)CN1S(=O)(=O)c1ccccc1
Structure:
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