Reaction Details Report a problem with these data
Target
Free fatty acid receptor 4
Ligand
BDBM369417
Substrate
n/a
Meas. Tech.
Beta arrestin 2 Interaction Assay (BRET assay)
EC50
260±n/a nM
Citation
 Kumar, S; Sharma, R; Halder, S; Sawargave, SP; Deore, VB Compounds for use as GPR120 agonists US Patent  US10227360 Publication Date 3/12/2019 
Target
Name:
Free fatty acid receptor 4
Synonyms:
FFAR4 | FFAR4_HUMAN | G-protein coupled receptor 120 | G-protein coupled receptor 129 | G-protein coupled receptor GT01 | G-protein coupled receptor PGR4 | GPR120 | GPR129 | O3FAR1 | Omega-3 fatty acid receptor 1 | PGR4
Type:
PROTEIN
Mol. Mass.:
42256.91
Organism:
Homo sapiens (Human)
Description:
ChEMBL_1508994
Residue:
377
Sequence:
MSPECARAAGDAPLRSLEQANRTRFPFFSDVKGDHRLVLAAVETTVLVLIFAVSLLGNVCALVLVARRRRRGATACLVLNLFCADLLFISAIPLVLAVRWTEAWLLGPVACHLLFYVMTLSGSVTILTLAAVSLERMVCIVHLQRGVRGPGRRARAVLLALIWGYSAVAALPLCVFFRVVPQRLPGADQEISICTLIWPTIPGEISWDVSFVTLNFLVPGLVIVISYSKILQTSEHLLDARAVVTHSEITKASRKRLTVSLAYSESHQIRVSQQDFRLFRTLFLLMVSFFIMWSPIIITILLILIQNFKQDLVIWPSLFFWVVAFTFANSALNPILYNMTLCRNEWKKIFCCFWFPEKGAILTDTSVKRNDLSIISG
  
Inhibitor
Name:
BDBM369417
Synonyms:
4-(4-((2-(5-Cyclopropylthiophen-2-yl)-5-fluorobenzyl)oxy)phenyl)butanoic acid | US10227360, Example 11
Type:
Small organic molecule
Emp. Form.:
C24H23FO3S
Mol. Mass.:
410.501
SMILES:
OC(=O)CCCc1ccc(OCc2cc(F)ccc2-c2ccc(s2)C2CC2)cc1
Structure:
Search PDB for entries with ligand similarity: