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Target
Mu-type opioid receptor
Ligand
BDBM369488
Substrate
n/a
Meas. Tech.
Opioid Receptor Binding Assay
EC50
2.30±n/a nM
Citation
 Blumberg, LC; Deaver, DR; Eyerman, DJ; Wynn, TA Methods for treating depressive symptoms US Patent  US10231963 Publication Date 3/19/2019 
Target
Name:
Mu-type opioid receptor
Synonyms:
M-OR-1 | MOP | MOR-1 | MOR1 | MUOR1 | Mu Opioid Receptor | Mu opiate receptor | OPIATE Mu | OPRM1 | OPRM_HUMAN | hMOP | mu-type opioid receptor isoform MOR-1
Type:
G Protein-Coupled Receptor (GPCR)
Mol. Mass.:
44789.51
Organism:
Homo sapiens (Human)
Description:
P35372
Residue:
400
Sequence:
MDSSAAPTNASNCTDALAYSSCSPAPSPGSWVNLSHLDGNLSDPCGPNRTDLGGRDSLCPPTGSPSMITAITIMALYSIVCVVGLFGNFLVMYVIVRYTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKIINVCNWILSSAIGLPVMFMATTKYRQGSIDCTLTFSHPTWYWENLLKICVFIFAFIMPVLIITVCYGLMILRLKSVRMLSGSKEKDRNLRRITRMVLVVVAVFIVCWTPIHIYVIIKALVTIPETTFQTVSWHFCIALGYTNSCLNPVLYAFLDENFKRCFREFCIPTSSNIEQQNSTRIRQNTRDHPSTANTVDRTNHQLENLEAETAPLP
  
Inhibitor
Name:
BDBM369488
Synonyms:
US10231963, Table B.28 | US10736890, Compound TABLE B.28 | US11534436, Compound Table B.28
Type:
Small organic molecule
Emp. Form.:
C19H27NO
Mol. Mass.:
285.4238
SMILES:
C[C@H](C1CC1)N1CC[C@@]2(C)[C@@H](C)[C@H]1Cc1ccc(O)cc21 |r,TLB:1:5:10:20.14.13|
Structure:
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