Reaction Details Report a problem with these data
Target
Free fatty acid receptor 4
Ligand
BDBM261524
Substrate
n/a
Meas. Tech.
FLIPR Assay
EC50
948±n/a nM
Citation
 Chelliah, M; Chu, HD; Cox, JM; Debenham, JS; Eagen, K; Lan, P; London, C; Plotkin, MA; Shah, U; Sinz, CJ; Sun, Z; Vaccaro, HM; Venkatraman, S Substituted spiropiperidinyl compounds useful as GPR120 agonists US Patent  US9708270 Publication Date 7/18/2017 
Target
Name:
Free fatty acid receptor 4
Synonyms:
FFAR4 | FFAR4_HUMAN | G-protein coupled receptor 120 | G-protein coupled receptor 129 | G-protein coupled receptor GT01 | G-protein coupled receptor PGR4 | GPR120 | GPR129 | O3FAR1 | Omega-3 fatty acid receptor 1 | PGR4
Type:
PROTEIN
Mol. Mass.:
42256.91
Organism:
Homo sapiens (Human)
Description:
ChEMBL_1508994
Residue:
377
Sequence:
MSPECARAAGDAPLRSLEQANRTRFPFFSDVKGDHRLVLAAVETTVLVLIFAVSLLGNVCALVLVARRRRRGATACLVLNLFCADLLFISAIPLVLAVRWTEAWLLGPVACHLLFYVMTLSGSVTILTLAAVSLERMVCIVHLQRGVRGPGRRARAVLLALIWGYSAVAALPLCVFFRVVPQRLPGADQEISICTLIWPTIPGEISWDVSFVTLNFLVPGLVIVISYSKILQTSEHLLDARAVVTHSEITKASRKRLTVSLAYSESHQIRVSQQDFRLFRTLFLLMVSFFIMWSPIIITILLILIQNFKQDLVIWPSLFFWVVAFTFANSALNPILYNMTLCRNEWKKIFCCFWFPEKGAILTDTSVKRNDLSIISG
  
Inhibitor
Name:
BDBM261524
Synonyms:
US9708270, 19
Type:
Small organic molecule
Emp. Form.:
C20H29NO2
Mol. Mass.:
315.4498
SMILES:
Cc1cc(C)cc(c1)N1CCC2(CCC(CC(O)=O)CC2)CC1
Structure:
Search PDB for entries with ligand similarity: