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Target
Vascular endothelial growth factor A
Ligand
BDBM373052
Substrate
n/a
Meas. Tech.
ELISA Assay
EC50
52.0±n/a nM
Citation
 Dixon, DD; Grina, J; Josey, JA; Rizzi, JP; Schlachter, ST; Wallace, EM; Wang, B; Wehn, P; Xu, R; Yang, H Aryl ethers and uses thereof US Patent  US9908845 Publication Date 3/6/2018 
Target
Name:
Vascular endothelial growth factor A
Synonyms:
VEGF | VEGF-A | VEGFA | VEGFA_HUMAN | VPF | Vascular endothelial growth factor (VEGF) | Vascular endothelial growth factor A (VEGF) | Vascular endothelial growth factor A (VEGF2) | Vascular permeability factor
Type:
Protein
Mol. Mass.:
27063.81
Organism:
Homo sapiens (Human)
Description:
P15692
Residue:
232
Sequence:
MNFLLSWVHWSLALLLYLHHAKWSQAAPMAEGGGQNHHEVVKFMDVYQRSYCHPIETLVDIFQEYPDEIEYIFKPSCVPLMRCGGCCNDEGLECVPTEESNITMQIMRIKPHQGQHIGEMSFLQHNKCECRPKKDRARQEKKSVRGKGKGQKRKRKKSRYKSWSVYVGARCCLMPWSLPGPHPCGPCSERRKHLFVQDPQTCKCSCKNTDSRCKARQLELNERTCRCDKPRR
  
Inhibitor
Name:
BDBM373052
Synonyms:
US10597366, Compound 342 | US9896418, Compound 342
Type:
Small organic molecule
Emp. Form.:
C16H11F3N2O4S
Mol. Mass.:
384.33
SMILES:
CS(=O)(=O)c1ccc(Oc2cncc(c2)C#N)c2[C@@H](F)C(F)(F)[C@@H](O)c12 |r|
Structure:
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