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TargetAryl Hydrocarbon Receptor (AhR)
LigandBDBM23945
Substrate/CompetitorBDBM23927
Meas. Tech.In Vitro Binding Assay
pH7.6±n/a
Temperature277.15±n/a K
Ki 96±3.4 nM
CommentsAntagonist.
Citation de Medina, PCasper, RSavouret, JFPoirot, M Synthesis and biological properties of new stilbene derivatives of resveratrol as new selective aryl hydrocarbon modulators. J Med Chem48:287-91 (2005) [PubMed]  Article
More Info.:Get all data from this article,   Solution Info,  Assay Method
 
Aryl Hydrocarbon Receptor (AhR)
Name:Aryl Hydrocarbon Receptor (AhR)
Synonyms:Dioxin receptor
Type:Transcription factor
Mol. Mass.:94428.00
Organism:Oryctolagus cuniculus (rabbit)
Description:Cytosols from rabbit liver were used in binding assay.
Residue:847
Sequence:
MNGGGANITYASRKRRKPVQKTVKPIPAEGIKSNPSKRHRDRLNTELDRLASLLPFPQDV
INKLDKLSVLRLSVSYLRAKSFFDVALKSSSADRNGGQDPCRAKFGEGLNLQEGEFLLQA
LNGFVLVVTVDALVFYASSTIQDYLGFQQSDVIHQSVYELIHTEDRAEFQRQLHWALNPS
QCTDPGQGADETHGLPQPVYYNPDQLPPENSSFMERCFICRLRCLLDNSSGFLAMNFQGR
LKFLHGQNKKGKDGSLLPPQLALFAIATPLQPPSILEIRTKNFIFRTKHKLDFTPTGCDA
KGQIVLGYTEAELCMRGSGYQFIHAADMLYCAESHIRMIKTGESGLAVFRLLTKDNRWAW
VQSNARFIYKNGRPDFIIATQRPLTDEEGREHLLKRNTKLPFMFTTGEAVLYEMTSPFPP
IMDPLPIRPKSGTCGKDSATKPTPSKDSVHPSSLLSALMQQDESIYLYPPSSNAPFERNF
FTESLNECSNWPENVASVAGGSVLKHEQIGQSQEVSPAFSGDQTVLFPDNKNCDLYNIMK
NLGVDFEDIKNMQNEEFFGADFSGEVDFRDIDITDEILTYVQDSLNKSPFGSPGYQPQPA
TALNSSCMVQERLQLGPPQQPPCRSEQATVEPQQQLCQKMEHMQVNSMFANWSANQPVPF
SEPQQDLQPYSVFTDFHTADQAFPYTAAMNTMPYTQNFTPCNQTVAPQHSRCTQLDFAMG
NFDSSPYPSTSNLEDFVTCLQVPDRQTHGGNPQSAMVAPQTCYAGAVSMYQCQPGPAHTL
MGQMQCEPPVPGPEAFLNKFPNGGMLNETYPADLHDINNTVASTHLPPLHHPSEARPFPD
LASGRLL
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  Blast E-value cutoff:
BDBM23945
NameBDBM23945
Synonyms:1-[(Z)-2-(4-fluorophenyl)ethenyl]-3,5-dimethoxybenzene | cis-Stilbene Derivative, 5f
TypeSmall organic molecule
Emp. Form.C16H15FO2
Mol. Mass.258.2875
SMILESCOc1cc(OC)cc(\C=C/c2ccc(F)cc2)c1
Structure
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BDBM23927
NameBDBM23927
Synonyms:2,3,7,8-Tetrachlorodibenzo-p-dioxin | 2,3,7,8-tetrachlorooxanthrene | Tetrachlorodibenzodioxin | [3H]-TCDD
Typeradiolabeled ligand
Emp. Form.C12H4Cl4O2
Mol. Mass.321.971
SMILESClc1cc2Oc3cc(Cl)c(Cl)cc3Oc2cc1Cl
Structure
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