Reaction Details Report a problem with these data
Target
Free fatty acid receptor 4
Ligand
BDBM382140
Substrate
n/a
Meas. Tech.
BRET assay
EC50
2750±n/a nM
Citation
 Kumar, S; Sharma, R; Deore, VB; Yewalkar, NN Substituted phenyl alkanoic acid compounds as GPR120 agonists and uses thereof US Patent  US10273230 Publication Date 4/30/2019 
Target
Name:
Free fatty acid receptor 4
Synonyms:
FFAR4 | FFAR4_HUMAN | G-protein coupled receptor 120 | G-protein coupled receptor 129 | G-protein coupled receptor GT01 | G-protein coupled receptor PGR4 | GPR120 | GPR129 | O3FAR1 | Omega-3 fatty acid receptor 1 | PGR4
Type:
PROTEIN
Mol. Mass.:
42256.91
Organism:
Homo sapiens (Human)
Description:
ChEMBL_1508994
Residue:
377
Sequence:
MSPECARAAGDAPLRSLEQANRTRFPFFSDVKGDHRLVLAAVETTVLVLIFAVSLLGNVCALVLVARRRRRGATACLVLNLFCADLLFISAIPLVLAVRWTEAWLLGPVACHLLFYVMTLSGSVTILTLAAVSLERMVCIVHLQRGVRGPGRRARAVLLALIWGYSAVAALPLCVFFRVVPQRLPGADQEISICTLIWPTIPGEISWDVSFVTLNFLVPGLVIVISYSKILQTSEHLLDARAVVTHSEITKASRKRLTVSLAYSESHQIRVSQQDFRLFRTLFLLMVSFFIMWSPIIITILLILIQNFKQDLVIWPSLFFWVVAFTFANSALNPILYNMTLCRNEWKKIFCCFWFPEKGAILTDTSVKRNDLSIISG
  
Inhibitor
Name:
BDBM382140
Synonyms:
4-(4-((4'-(1-cyanocyclopropyl)-4-methyl-3,4,5,6-tetrahydro-[1,1'-biphenyl]-2-yl) methoxy) phenyl)butanoic Acid | US10273230, Compound of Example 53
Type:
Small organic molecule
Emp. Form.:
C29H33NO2
Mol. Mass.:
427.5778
SMILES:
CC(C1=C(CCC(C)C1)c1ccc(cc1)C1(CC1)C#N)c1ccc(CCCC(O)=O)cc1 |t:2|
Structure:
Search PDB for entries with ligand similarity: