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Target
Transthyretin
Ligand
BDBM50017846
Substrate
n/a
Meas. Tech.
The FP assay
IC50
741±n/a nM
Citation
 Graef, IA; Alhamadsheh, MM Identification of stabilizers of multimeric proteins US Patent  US10278929 Publication Date 5/7/2019 
Target
Name:
Transthyretin
Synonyms:
ATTR | PALB | Prealbumin | TBPA | TTHY_HUMAN | TTR | Transthyretin (TTR)
Type:
Enzyme
Mol. Mass.:
15884.31
Organism:
Homo sapiens (Human)
Description:
P02766
Residue:
147
Sequence:
MASHRLLLLCLAGLVFVSEAGPTGTGESKCPLMVKVLDAVRGSPAINVAVHVFRKAADDTWEPFASGKTSESGELHGLTTEEEFVEGIYKVEIDTKSYWKALGISPFHEHAEVVFTANDSGPRRYTIAALLSPYSYSTTAVVTNPKE
  
Inhibitor
Name:
BDBM50017846
Synonyms:
3,5-DINITROCATECHOL | 3,5-Dinitro-benzene-1,2-diol | CHEMBL168276 | US10278929, 3,5-dinitrocatecol | US11337935, 3,5-dinitrocatechol
Type:
Small organic molecule
Emp. Form.:
C6H4N2O6
Mol. Mass.:
200.1058
SMILES:
Oc1cc(cc(c1O)[N+]([O-])=O)[N+]([O-])=O
Structure:
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