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Target
Protein Wnt-3a
Ligand
BDBM263584
Substrate
n/a
Meas. Tech.
WNT Pathway Reporter Gene Assay
IC50
<3.00±n/a nM
Citation
 An, S Compounds for treatment of fibrosis diseases US Patent  US10285988 Publication Date 5/14/2019 
Target
Name:
Protein Wnt-3a
Synonyms:
WNT3A | WNT3A_HUMAN
Type:
PROTEIN
Mol. Mass.:
39379.02
Organism:
Homo sapiens (Human)
Description:
ChEMBL_1469237
Residue:
352
Sequence:
MAPLGYFLLLCSLKQALGSYPIWWSLAVGPQYSSLGSQPILCASIPGLVPKQLRFCRNYVEIMPSVAEGIKIGIQECQHQFRGRRWNCTTVHDSLAIFGPVLDKATRESAFVHAIASAGVAFAVTRSCAEGTAAICGCSSRHQGSPGKGWKWGGCSEDIEFGGMVSREFADARENRPDARSAMNRHNNEAGRQAIASHMHLKCKCHGLSGSCEVKTCWWSQPDFRAIGDFLKDKYDSASEMVVEKHRESRGWVETLRPRYTYFKVPTERDLVYYEASPNFCEPNPETGSFGTRDRTCNVSSHGIDGCDLLCCGRGHNARAERRREKCRCVFHWCCYVSCQECTRVYDVHTCK
  
Inhibitor
Name:
BDBM263584
Synonyms:
US10087181, Compound 28 | US10285988, Compound 28 | US9713612, 28
Type:
Small organic molecule
Emp. Form.:
C26H19F2N5
Mol. Mass.:
439.4594
SMILES:
Cc1cc(ccn1)-c1cc2ccnc(NCc3ccc(c(F)c3)-c3ccnc(F)c3)c2cn1
Structure:
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