Target
Mu-type opioid receptor
Ligand
BDBM179881
Substrate
n/a
Meas. Tech.
Opioid Receptor Binding Assay
IC50
51.0±n/a nM
Citation
 Blumberg, LCDeaver, DREyerman, DJWynn, TA Morphan and morphinan analogues, and methods of use US Patent  US10287250 Publication Date 5/14/2019 
Target
Name:
Mu-type opioid receptor
Synonyms:
M-OR-1 | MOP | MOR-1 | MOR1 | MUOR1 | Mu Opioid Receptor | Mu opiate receptor | OPIATE Mu | OPRM1 | OPRM_HUMAN | hMOP | mu-type opioid receptor isoform MOR-1
Type:
G Protein-Coupled Receptor (GPCR)
Mol. Mass.:
44789.51
Organism:
Homo sapiens (Human)
Description:
P35372
Residue:
400
Sequence:
MDSSAAPTNASNCTDALAYSSCSPAPSPGSWVNLSHLDGNLSDPCGPNRTDLGGRDSLCPPTGSPSMITAITIMALYSIVCVVGLFGNFLVMYVIVRYTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKIINVCNWILSSAIGLPVMFMATTKYRQGSIDCTLTFSHPTWYWENLLKICVFIFAFIMPVLIITVCYGLMILRLKSVRMLSGSKEKDRNLRRITRMVLVVVAVFIVCWTPIHIYVIIKALVTIPETTFQTVSWHFCIALGYTNSCLNPVLYAFLDENFKRCFREFCIPTSSNIEQQNSTRIRQNTRDHPSTANTVDRTNHQLENLEAETAPLP
  
Inhibitor
Name:
BDBM179881
Synonyms:
US10231963, Table B.27 | US10287250, Compound B.9 | US10736890, Compound TABLE B.27 | US10752592, Compound TABLE B.9 | US11534436, Compound Table B.27 | US9133125, Table B, Compound 9 | US9656961, Example 00144
Type:
Small organic molecule
Emp. Form.:
C23H30N2O3
Mol. Mass.:
382.4959
SMILES:
[#6]\[#6](-[#6])=[#6]\[#6]-[#7]-1-[#6]-[#6][C@]23[#6]-[#6](=[#6])-[#6]-[#6][C@@]2([#8])[#6@H]-1-[#6]-c1ccc(-[#6](-[#7])=O)c(-[#8])c31 |r|
Structure:
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