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Target
Mu-type opioid receptor
Ligand
BDBM179886
Substrate
n/a
Meas. Tech.
Opioid Receptor Binding Assay
Ki
4.60±n/a nM
Citation
 Blumberg, LC; Deaver, DR; Eyerman, DJ; Wynn, TA Morphan and morphinan analogues, and methods of use US Patent  US10287250 Publication Date 5/14/2019 
Target
Name:
Mu-type opioid receptor
Synonyms:
M-OR-1 | MOP | MOR-1 | MOR1 | MUOR1 | Mu Opioid Receptor | Mu opiate receptor | OPIATE Mu | OPRM1 | OPRM_HUMAN | hMOP | mu-type opioid receptor isoform MOR-1
Type:
G Protein-Coupled Receptor (GPCR)
Mol. Mass.:
44789.51
Organism:
Homo sapiens (Human)
Description:
P35372
Residue:
400
Sequence:
MDSSAAPTNASNCTDALAYSSCSPAPSPGSWVNLSHLDGNLSDPCGPNRTDLGGRDSLCPPTGSPSMITAITIMALYSIVCVVGLFGNFLVMYVIVRYTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKIINVCNWILSSAIGLPVMFMATTKYRQGSIDCTLTFSHPTWYWENLLKICVFIFAFIMPVLIITVCYGLMILRLKSVRMLSGSKEKDRNLRRITRMVLVVVAVFIVCWTPIHIYVIIKALVTIPETTFQTVSWHFCIALGYTNSCLNPVLYAFLDENFKRCFREFCIPTSSNIEQQNSTRIRQNTRDHPSTANTVDRTNHQLENLEAETAPLP
  
Inhibitor
Name:
BDBM179886
Synonyms:
US10287250, Compound C.4 | US10752592, Compound TABLE C.-10 | US9133125, Table C, Compound 4 | US9656961, Example 00150
Type:
Small organic molecule
Emp. Form.:
C18H27NO2
Mol. Mass.:
289.4125
SMILES:
CC1C2Cc3ccc(O)cc3[C@]1(C)CCN2CC(C)(C)O |r,TLB:16:15:1:10.4.3,9:10:1:13.15.14|
Structure:
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