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Target
Mu-type opioid receptor
Ligand
BDBM179892
Substrate
n/a
Meas. Tech.
Functional Assay (GTPgammaS Binding)
EC50
62.0±n/a nM
Citation
 Blumberg, LC; Deaver, DR; Eyerman, DJ; Wynn, TA Morphan and morphinan analogues, and methods of use US Patent  US10287250 Publication Date 5/14/2019 
Target
Name:
Mu-type opioid receptor
Synonyms:
M-OR-1 | MOP | MOR-1 | MOR1 | MUOR1 | Mu Opioid Receptor | Mu opiate receptor | OPIATE Mu | OPRM1 | OPRM_HUMAN | hMOP | mu-type opioid receptor isoform MOR-1
Type:
G Protein-Coupled Receptor (GPCR)
Mol. Mass.:
44789.51
Organism:
Homo sapiens (Human)
Description:
P35372
Residue:
400
Sequence:
MDSSAAPTNASNCTDALAYSSCSPAPSPGSWVNLSHLDGNLSDPCGPNRTDLGGRDSLCPPTGSPSMITAITIMALYSIVCVVGLFGNFLVMYVIVRYTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKIINVCNWILSSAIGLPVMFMATTKYRQGSIDCTLTFSHPTWYWENLLKICVFIFAFIMPVLIITVCYGLMILRLKSVRMLSGSKEKDRNLRRITRMVLVVVAVFIVCWTPIHIYVIIKALVTIPETTFQTVSWHFCIALGYTNSCLNPVLYAFLDENFKRCFREFCIPTSSNIEQQNSTRIRQNTRDHPSTANTVDRTNHQLENLEAETAPLP
  
Inhibitor
Name:
BDBM179892
Synonyms:
US10287250, Compound C.11 | US10752592, Compound TABLE C.-3 | US9133125, Table C, Compound 10 | US9133125, Table C, Compound 11 | US9656961, Example 00161
Type:
Small organic molecule
Emp. Form.:
C17H24N2O
Mol. Mass.:
272.3853
SMILES:
C[C@@]12CCCCC[C@@H](Cc3ccc(cc13)C(N)=O)[C@@H]2N |r|
Structure:
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