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Target
Mu-type opioid receptor
Ligand
BDBM179901
Substrate
n/a
Meas. Tech.
Opioid Receptor Binding Assay
Ki
0.120±n/a nM
Citation
 Blumberg, LC; Deaver, DR; Eyerman, DJ; Wynn, TA Morphan and morphinan analogues, and methods of use US Patent  US10287250 Publication Date 5/14/2019 
Target
Name:
Mu-type opioid receptor
Synonyms:
M-OR-1 | MOP | MOR-1 | MOR1 | MUOR1 | Mu Opioid Receptor | Mu opiate receptor | OPIATE Mu | OPRM1 | OPRM_HUMAN | hMOP | mu-type opioid receptor isoform MOR-1
Type:
G Protein-Coupled Receptor (GPCR)
Mol. Mass.:
44789.51
Organism:
Homo sapiens (Human)
Description:
P35372
Residue:
400
Sequence:
MDSSAAPTNASNCTDALAYSSCSPAPSPGSWVNLSHLDGNLSDPCGPNRTDLGGRDSLCPPTGSPSMITAITIMALYSIVCVVGLFGNFLVMYVIVRYTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKIINVCNWILSSAIGLPVMFMATTKYRQGSIDCTLTFSHPTWYWENLLKICVFIFAFIMPVLIITVCYGLMILRLKSVRMLSGSKEKDRNLRRITRMVLVVVAVFIVCWTPIHIYVIIKALVTIPETTFQTVSWHFCIALGYTNSCLNPVLYAFLDENFKRCFREFCIPTSSNIEQQNSTRIRQNTRDHPSTANTVDRTNHQLENLEAETAPLP
  
Inhibitor
Name:
BDBM179901
Synonyms:
US10231963, Table C.5 | US10287250, Compound 14 | US10736890, Compound TABLE C.5 | US10752592, Compound TABLE D.5 | US11534436, Compound Table C.5 | US9133125, Table D, Compound 14 | US9656961, Example 00169
Type:
Small organic molecule
Emp. Form.:
C18H26N2O2
Mol. Mass.:
302.4112
SMILES:
COCCN1CC[C@]2(C)[C@@H](C)[C@H]1Cc1ccc(cc21)C(N)=O |r,TLB:3:4:9:18.13.12|
Structure:
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