Reaction Details Report a problem with these data
Target
Fatty acid-binding protein, adipocyte
Ligand
BDBM263063
Substrate
n/a
Meas. Tech.
FABP Assay
pH
7.5±n/a
Temperature
298.15±n/a K
IC50
11070±n/a nM
Comments
extracted
Citation
 Buettelmann, B; Ceccarelli, SM; Conte, A; Kuehne, H; Kuhn, B; Neidhart, W; Sander, UO; Richter, H Urea derivatives and their use as fatty-acid binding protein (FABP) inhibitors US Patent  US9708340 Publication Date 7/18/2017 
Target
Name:
Fatty acid-binding protein, adipocyte
Synonyms:
A-FABP | AFABP | ALBP | Adipocyte lipid-binding protein | FABP4 | FABP4_HUMAN | Fatty acid binding protein adipocyte | Fatty acid-binding protein 4 | Fatty acid-binding protein 4 (FABP4)
Type:
Enzyme
Mol. Mass.:
14719.23
Organism:
Homo sapiens (Human)
Description:
P15090
Residue:
132
Sequence:
MCDAFVGTWKLVSSENFDDYMKEVGVGFATRKVAGMAKPNMIISVNGDVITIKSESTFKNTEISFILGQEFDEVTADDRKVKSTITLDGGVLVHVQKWDGKSTTIKRKREDDKLVVECVMKGVTSTRVYERA
  
Inhibitor
Name:
BDBM263063
Synonyms:
US9708340, 56
Type:
Small organic molecule
Emp. Form.:
C19H18ClN3O4
Mol. Mass.:
387.817
SMILES:
NC(=O)c1cccc(c1)-c1ccc(Cl)cc1NC(=O)N1CCC[C@@H]1C(O)=O |r|
Structure:
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