Reaction Details Report a problem with these data
Target
Free fatty acid receptor 4
Ligand
BDBM386964
Substrate
n/a
Meas. Tech.
GPR120 pERK assay
EC50
300±n/a nM
Citation
 Shi, Y; Cheng, PT; Wang, Y; Jusuf, S; Tao, S; Zhang, H; Wu, SC; Robl, JA Cyclopropanecarboxylic acid GPR120 modulators US Patent  US9938222 Publication Date 4/10/2018 
Target
Name:
Free fatty acid receptor 4
Synonyms:
FFAR4 | FFAR4_HUMAN | G-protein coupled receptor 120 | G-protein coupled receptor 129 | G-protein coupled receptor GT01 | G-protein coupled receptor PGR4 | GPR120 | GPR129 | O3FAR1 | Omega-3 fatty acid receptor 1 | PGR4
Type:
PROTEIN
Mol. Mass.:
42256.91
Organism:
Homo sapiens (Human)
Description:
ChEMBL_1508994
Residue:
377
Sequence:
MSPECARAAGDAPLRSLEQANRTRFPFFSDVKGDHRLVLAAVETTVLVLIFAVSLLGNVCALVLVARRRRRGATACLVLNLFCADLLFISAIPLVLAVRWTEAWLLGPVACHLLFYVMTLSGSVTILTLAAVSLERMVCIVHLQRGVRGPGRRARAVLLALIWGYSAVAALPLCVFFRVVPQRLPGADQEISICTLIWPTIPGEISWDVSFVTLNFLVPGLVIVISYSKILQTSEHLLDARAVVTHSEITKASRKRLTVSLAYSESHQIRVSQQDFRLFRTLFLLMVSFFIMWSPIIITILLILIQNFKQDLVIWPSLFFWVVAFTFANSALNPILYNMTLCRNEWKKIFCCFWFPEKGAILTDTSVKRNDLSIISG
  
Inhibitor
Name:
BDBM386964
Synonyms:
Trans-2-(((5′-((R)-sec-butoxy)-2′-fluoro-[1,1′-biphenyl]-4-yl)oxy)methyl) cyclopropanecarboxylic acid | US9938222, Example 93
Type:
Small organic molecule
Emp. Form.:
C21H23FO4
Mol. Mass.:
358.4033
SMILES:
CC[C@@H](C)Oc1ccc(F)c(c1)-c1ccc(OCC2CC2C(O)=O)cc1 |r|
Structure:
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