Reaction Details Report a problem with these data
Target
Interleukin-6
Ligand
BDBM77001
Substrate
n/a
Meas. Tech.
cytomteric bead array (CBA) assay
Temperature
310.15±n/a K
IC50
10.00±n/a nM
Comments
extracted
Citation
 Gandhi, A; Dimartino, J; Chopra, R Methods for the treatment of locally advanced breast cancer US Patent  US9694015 Publication Date 7/4/2017 
Target
Name:
Interleukin-6
Synonyms:
B-cell stimulatory factor 2 | BSF-2 | CDF | CTL differentiation factor | Hybridoma growth factor | IFN-beta-2 | IFNB2 | IL-6 | IL6 | IL6_HUMAN | Interferon beta-2
Type:
n/a
Mol. Mass.:
23717.96
Organism:
Homo sapiens (Human)
Description:
P05231
Residue:
212
Sequence:
MNSFSTSAFGPVAFSLGLLLVLPAAFPAPVPPGEDSKDVAAPHRQPLTSSERIDKQIRYILDGISALRKETCNKSNMCESSKEALAENNLNLPKMAEKDGCFQSGFNEETCLVKIITGLLEFEVYLEYLQNRFESSEEQARAVQMSTKVLIQFLQKKAKNLDAITTPDPTTNASLLTKLQAQNQWLQDMTTHLILRSFKEFLQSSLRALRQM
  
Inhibitor
Name:
BDBM77001
Synonyms:
3-(4-((4-(morpholinomethyl)benzyl)-oxy)-1-oxoisoindolin-2-yl)piperidine-2,6-dione | US9694015, 6.4
Type:
Small organic molecule
Emp. Form.:
C25H27N3O5
Mol. Mass.:
449.499
SMILES:
O=C1N(Cc2c1cccc2OCc1ccc(CN2CCOCC2)cc1)C1CCC(=O)NC1=O
Structure:
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