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Target
Glyceraldehyde-3-phosphate dehydrogenase, cytosolic
Ligand
BDBM50070114
Substrate
n/a
Meas. Tech.
cytomteric bead array (CBA) assay
Temperature
310.15±n/a K
IC50
>10000±n/a nM
Comments
extracted
Citation
 Gandhi, A; Dimartino, J; Chopra, R Methods for the treatment of locally advanced breast cancer US Patent  US9694015 Publication Date 7/4/2017 
Target
Name:
Glyceraldehyde-3-phosphate dehydrogenase, cytosolic
Synonyms:
G3PC_LEIME | GAPC | GAPDH | Glyceraldehyde-3-phosphate dehydrogenase cytosolic | Glyceraldehyde-3-phosphate dehydrogenase, cytosolic
Type:
PROTEIN
Mol. Mass.:
35645.40
Organism:
Leishmania mexicana
Description:
ChEMBL_72768
Residue:
331
Sequence:
MVKVGINGFGRIGRVVFRAAQMRPDIEIVGINDLLDAEYMAYSLKYDSTHGRFDGTVEVIKGALVVNGKSIRVTSERDPANLKWDEIGVEVVVESTGLFLTQETAHKHIEAGARRVVMTGPPKDDTPMFVMGVNHTTYKGQPIISNASCTTNCLAPLAKVVNEKYGIVEGLMTTVHATTATQKTVDGPSLKDWRGGRGASQNIIPSSTGAPKAVGKVYPALDGKLTGMAFRVPTPNVSVVDLTVRLEKPATYKDICAAIKAAAEGEMKGILGYTDDEVVSSDFNGVALTSVFDVKAGISLNDHFVKLVSWYDNETGYSHKVLDLILHTSAR
  
Inhibitor
Name:
BDBM50070114
Synonyms:
(+/-)-thalidomide | 2-(2,6-Dioxo-piperidin-3-yl)-isoindole-1,3-dione | 2-(2,6-dioxopiperidin-3-yl)isoindoline-1,3-dione | CHEMBL468 | K-17 | THALIDOMIDE | Thalomid | US11059801, Compound D-62 | [(R,S)-2-(2,6-dioxo-3-piperidinyl)-1H-isoindole-1,3(2H)-dione
Type:
Small organic molecule
Emp. Form.:
C13H10N2O4
Mol. Mass.:
258.2295
SMILES:
O=C1N(C2CCC(=O)NC2=O)C(=O)c2ccccc12
Structure:
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