Reaction Details Report a problem with these data
Target
Trace amine-associated receptor 1
Ligand
BDBM390680
Substrate
n/a
Meas. Tech.
Radioligand Binding
Ki
15.9±n/a nM
Citation
 Cecere, G; Galley, G; Goergler, A; Norcross, R; Pflieger, P; Tirla, A; Schmid, P 6-amino-5,6,7,8-tetrahydronaphthalen-2-yl or 3-aminochroman-7-yl derivatives US Patent  US9957261 Publication Date 5/1/2018 
Target
Name:
Trace amine-associated receptor 1
Synonyms:
TAAR1_MOUSE | Ta1 | Taar1 | Tar1 | Trace amine receptor 1 (TARR1) | Trace amine-associated receptor 1 (TAAR1) | Trace amine-associated receptor1 | Trar1
Type:
Protein
Mol. Mass.:
37635.41
Organism:
Mus musculus (Mouse)
Description:
Q923Y8
Residue:
332
Sequence:
MHLCHAITNISHRNSDWSREVQASLYSLMSLIILATLVGNLIVIISISHFKQLHTPTNWLLHSMAIVDFLLGCLIMPCSMVRTVERCWYFGEILCKVHTSTDIMLSSASIFHLAFISIDRYCAVCDPLRYKAKINISTILVMILVSWSLPAVYAFGMIFLELNLKGVEELYRSQVSDLGGCSPFFSKVSGVLAFMTSFYIPGSVMLFVYYRIYFIAKGQARSINRTNVQVGLEGKSQAPQSKETKAAKTLGIMVGVFLVCWCPFFLCTVLDPFLGYVIPPSLNDALYWFGYLNSALNPMVYAFFYPWFRRALKMVLLGKIFQKDSSRSKLFL
  
Inhibitor
Name:
BDBM390680
Synonyms:
N-(6-Amino-5,6,7,8-tetrahydronaphthalen-2-yl)-2-(trifluoromethyl)isonicotinamide | US9957261, Example 1
Type:
Small organic molecule
Emp. Form.:
C17H16F3N3O
Mol. Mass.:
335.3236
SMILES:
NC1CCc2cc(NC(=O)c3ccnc(c3)C(F)(F)F)ccc2C1
Structure:
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