Reaction Details Report a problem with these data
Target
Trace amine-associated receptor 1
Ligand
BDBM390720
Substrate
n/a
Meas. Tech.
Radioligand Binding
Ki
302±n/a nM
Citation
 Cecere, G; Galley, G; Goergler, A; Norcross, R; Pflieger, P; Tirla, A; Schmid, P 6-amino-5,6,7,8-tetrahydronaphthalen-2-yl or 3-aminochroman-7-yl derivatives US Patent  US9957261 Publication Date 5/1/2018 
Target
Name:
Trace amine-associated receptor 1
Synonyms:
TAAR1_RAT | Ta1 | Taar1 | Tar1 | Trace amine receptor 1 (TARR1) | Trace amine-associated receptor 1 | Trace amine-associated receptor 1 (TAAR1) | Trace amine-associated receptor1 | Trar1
Type:
Enzyme
Mol. Mass.:
38034.73
Organism:
Rattus norvegicus (Rat)
Description:
Q923Y9
Residue:
332
Sequence:
MHLCHNSANISHTNSNWSRDVRASLYSLISLIILTTLVGNLIVIISISHFKQLHTPTNWLLHSMAVVDFLLGCLVMPYSMVRTVEHCWYFGELFCKLHTSTDIMLSSASILHLAFISIDRYYAVCDPLRYKAKINLAAIFVMILISWSLPAVFAFGMIFLELNLEGVEELYHNQVFCLRGCFPFFSKVSGVLAFMTSFYIPGSVMLFVYYRIYFIAKGQARSINRANLQVGLEGESRAPQSKETKAAKTLGIMVGVFLLCWCPFFFCMVLDPFLGYVIPPTLNDTLNWFGYLNSAFNPMVYAFFYPWFRRALKMVLFGKIFQKDSSRSKLFL
  
Inhibitor
Name:
BDBM390720
Synonyms:
(S)-N-(6-Amino-1-chloro-5,6,7,8-tetrahydronaphthalen-2-yl)-6-chloronicotinamide | US9957261, Example 76
Type:
Small organic molecule
Emp. Form.:
C16H15Cl2N3O
Mol. Mass.:
336.216
SMILES:
N[C@H]1CCc2c(C1)ccc(NC(=O)c1ccc(Cl)nc1)c2Cl |r|
Structure:
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