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Target
Melanocortin receptor 3
Ligand
BDBM392686
Substrate
n/a
Meas. Tech.
Test for Evaluating Human MC Receptor Activation, Using Cells Expressing Human MC4, MC1, or MC3 Receptor
EC50
680±n/a nM
Citation
 Sugane, T; Makino, T; Yamashita, D; Yonetoku, Y; Tanabe, D; Mihara, H; Asai, N; Osoda, K; Shimizu, T; Moritomo, H; Sugasawa, K; Maeno, K; Hosogai, N Piperazine derivative US Patent  US10301286 Publication Date 5/28/2019 
Target
Name:
Melanocortin receptor 3
Synonyms:
MC3-R | MC3R | MC3R_HUMAN | Melanocortin MC3 | Melanocortin receptor (M3 and M4)
Type:
Enzyme
Mol. Mass.:
36044.86
Organism:
Homo sapiens (Human)
Description:
P41968
Residue:
323
Sequence:
MNASCCLPSVQPTLPNGSEHLQAPFFSNQSSSAFCEQVFIKPEVFLSLGIVSLLENILVILAVVRNGNLHSPMYFFLCSLAVADMLVSVSNALETIMIAIVHSDYLTFEDQFIQHMDNIFDSMICISLVASICNLLAIAVDRYVTIFYALRYHSIMTVRKALTLIVAIWVCCGVCGVVFIVYSESKMVIVCLITMFFAMMLLMGTLYVHMFLFARLHVKRIAALPPADGVAPQQHSCMKGAVTITILLGVFIFCWAPFFLHLVLIITCPTNPYCICYTAHFNTYLVLIMCNSVIDPLIYAFRSLELRNTFREILCGCNGMNLG
  
Inhibitor
Name:
BDBM392686
Synonyms:
US10301286, Example 78
Type:
Small organic molecule
Emp. Form.:
C32H41ClFN3O4
Mol. Mass.:
586.137
SMILES:
C[C@H]([C@H](N1CCN([C@@H](C)C1)C(=O)[C@@H]1CN(C[C@H]1c1ccc(Cl)cc1F)C1CCOCC1)C(O)=O)c1ccc(C)cc1 |r|
Structure:
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