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Target
Eyes absent homolog 3 [223-510]
Ligand
BDBM50342278
Substrate
n/a
Meas. Tech.
Inhibition Assay
IC50
19200±n/a nM
Citation
 Hegde, R Use of small molecule inhibitors targeting EYA tyrosine phosphatase US Patent  US9962362 Publication Date 5/8/2018 
Target
Name:
Eyes absent homolog 3 [223-510]
Synonyms:
EYA3(ED) | EYA3_MOUSE | Eya3
Type:
Protein
Mol. Mass.:
32106.87
Organism:
Mus musculus (Mouse)
Description:
P97480 (aa223-510)
Residue:
288
Sequence:
NRGKRKADASSSQDSELERVFLWDLDETIIIFHSLLTGSYAQKYGKDPTVVIGSGLTMEEMIFEVADTHLFFNDLEECDQVHVEDVASDDNGQDLSNYSFSTDGFSGSGGSGSHGSSVGVQGGVDWMRKLAFRYRKVREIYDKHKSNVGGLLSPQRKEALQRLRAEIEVLTDSWLGTALKSLLLIQSRKNCANVLITTTQLVPALAKVLLYGLGEIFPIENIYSATKIGKESCFERIVSRFGKKVTYVVIGDGRDEEIAAKQHNMPFWRITNHGDLVSLHQALELDFL
  
Inhibitor
Name:
BDBM50342278
Synonyms:
(2-Ethylbenzofuran-3-yl)(4-hydroxyphenyl)methanone | Benzarone | CHEMBL1474963 | US9725430, Compound 1a | US9962362, Compound 1a
Type:
Small organic molecule
Emp. Form.:
C17H14O3
Mol. Mass.:
266.2913
SMILES:
CCc1oc2ccccc2c1C(=O)c1ccc(O)cc1
Structure:
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