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Target
Protein Wnt-3a
Ligand
BDBM263599
Substrate
n/a
Meas. Tech.
WNT Pathway Reporter Gene Assay
IC50
1.000±n/a nM
Citation
 An, S Compounds for treatment of cancer US Patent  US9713612 Publication Date 7/25/2017 
Target
Name:
Protein Wnt-3a
Synonyms:
WNT3A | WNT3A_HUMAN
Type:
PROTEIN
Mol. Mass.:
39379.02
Organism:
Homo sapiens (Human)
Description:
ChEMBL_1469237
Residue:
352
Sequence:
MAPLGYFLLLCSLKQALGSYPIWWSLAVGPQYSSLGSQPILCASIPGLVPKQLRFCRNYVEIMPSVAEGIKIGIQECQHQFRGRRWNCTTVHDSLAIFGPVLDKATRESAFVHAIASAGVAFAVTRSCAEGTAAICGCSSRHQGSPGKGWKWGGCSEDIEFGGMVSREFADARENRPDARSAMNRHNNEAGRQAIASHMHLKCKCHGLSGSCEVKTCWWSQPDFRAIGDFLKDKYDSASEMVVEKHRESRGWVETLRPRYTYFKVPTERDLVYYEASPNFCEPNPETGSFGTRDRTCNVSSHGIDGCDLLCCGRGHNARAERRREKCRCVFHWCCYVSCQECTRVYDVHTCK
  
Inhibitor
Name:
BDBM263599
Synonyms:
US10087181, Compound 97 | US10285988, Compound 97 | US9713612, 97
Type:
Small organic molecule
Emp. Form.:
C26H21FN6
Mol. Mass.:
436.4835
SMILES:
Cc1cc(ccn1)-c1cc2ccnc(NCc3cnc(c(F)c3)-c3ccnc(C)c3)c2cn1
Structure:
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