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Target
C-C chemokine receptor type 9
Ligand
BDBM393554
Substrate
n/a
Meas. Tech.
FLIPR Assay
Ki
51.0±n/a nM
Citation
 Bakthavatchalam, R; Basu, MK; Behera, AK; Venkateshappa, C; Hewson, CA; Kadnur, SV; Kalindjian, SB; Kulkarni, B; Saxena, R; Suresh, J; Viswanathan, V; Zainuddin, M; Dharshinis, AP; Kristam, R Compounds useful as CCR9 modulators US Patent  US9969687 Publication Date 5/15/2018 
Target
Name:
C-C chemokine receptor type 9
Synonyms:
CCR9 | CCR9_HUMAN | GPR28
Type:
PROTEIN
Mol. Mass.:
42023.90
Organism:
Homo sapiens (Human)
Description:
ChEMBL_1510356
Residue:
369
Sequence:
MTPTDFTSPIPNMADDYGSESTSSMEDYVNFNFTDFYCEKNNVRQFASHFLPPLYWLVFIVGALGNSLVILVYWYCTRVKTMTDMFLLNLAIADLLFLVTLPFWAIAAADQWKFQTFMCKVVNSMYKMNFYSCVLLIMCISVDRYIAIAQAMRAHTWREKRLLYSKMVCFTIWVLAAALCIPEILYSQIKEESGIAICTMVYPSDESTKLKSAVLTLKVILGFFLPFVVMACCYTIIIHTLIQAKKSSKHKALKVTITVLTVFVLSQFPYNCILLVQTIDAYAMFISNCAVSTNIDICFQVTQTIAFFHSCLNPVLYVFVGERFRRDLVKTLKNLGCISQAQWVSFTRREGSLKLSSMLLETTSGALSL
  
Inhibitor
Name:
BDBM393554
Synonyms:
US9969687, Compound 225
Type:
Small organic molecule
Emp. Form.:
C24H22ClN3O4S
Mol. Mass.:
483.967
SMILES:
Cc1ccnc(c1)N1C(=O)c2c(C1=O)c(NS(=O)(=O)c1ccc(cc1)C(C)(C)C)ccc2Cl
Structure:
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