Reaction Details Report a problem with these data
Target
Free fatty acid receptor 1
Ligand
BDBM393618
Substrate
n/a
Meas. Tech.
Activity Assay
EC50
>300±n/a nM
Citation
 Yang, J; Kim, JW; Lee, HK; Kim, JH; Son, CM; Lee, null; Choi, H; Kim, null; Ha, T; Rhee, J 3-(4-(benzyloxy)phenyl)hex-4-ynoic acid derivative, method of preparing same and pharmaceutical composition for preventing and treating metabolic disease including same as effective ingredient US Patent  US9969723 Publication Date 5/15/2018 
Target
Name:
Free fatty acid receptor 1
Synonyms:
FFAR1 | FFAR1_HUMAN | G-protein Coupled Receptor 40 | GPR40
Type:
G Protein-Coupled Receptor (GPCR)
Mol. Mass.:
31473.32
Organism:
Homo sapiens (Human)
Description:
O14842
Residue:
300
Sequence:
MDLPPQLSFGLYVAAFALGFPLNVLAIRGATAHARLRLTPSLVYALNLGCSDLLLTVSLPLKAVEALASGAWPLPASLCPVFAVAHFFPLYAGGGFLAALSAGRYLGAAFPLGYQAFRRPCYSWGVCAAIWALVLCHLGLVFGLEAPGGWLDHSNTSLGINTPVNGSPVCLEAWDPASAGPARFSLSLLLFFLPLAITAFCYVGCLRALARSGLTHRRKLRAAWVAGGALLTLLLCVGPYNASNVASFLYPNLGGSWRKLGLITGAWSVVLNPLVTGYLGRGPGLKTVCAARTQGGKSQK
  
Inhibitor
Name:
BDBM393618
Synonyms:
US9969723, 1
Type:
Small organic molecule
Emp. Form.:
C27H28O5
Mol. Mass.:
432.5082
SMILES:
CC#CC(CC(O)=O)c1ccc(OCc2cccc(c2)C2=CCC3(CC2)OCCO3)cc1 |t:21|
Structure:
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