Reaction Details Report a problem with these data
Target
D(3) dopamine receptor
Ligand
BDBM301790
Substrate
n/a
Meas. Tech.
Radioligand Binding Assay
Ki
0.390±0.10 nM
Citation
 Ananthan, S Urea and amide derivatives of aminoalkylpiperazines and use thereof US Patent  US9969743 Publication Date 5/15/2018 
Target
Name:
D(3) dopamine receptor
Synonyms:
DOPAMINE D3 | DRD3 | DRD3_HUMAN | Dopamine D3 receptor | Dopamine D3 receptor (D3) | Dopamine D3 receptor (D3R) | Dopamine receptor | Dopamine receptor (D3) | Dopamine receptor D3
Type:
n/a
Mol. Mass.:
44243.43
Organism:
Homo sapiens (Human)
Description:
n/a
Residue:
400
Sequence:
MASLSQLSSHLNYTCGAENSTGASQARPHAYYALSYCALILAIVFGNGLVCMAVLKERALQTTTNYLVVSLAVADLLVATLVMPWVVYLEVTGGVWNFSRICCDVFVTLDVMMCTASILNLCAISIDRYTAVVMPVHYQHGTGQSSCRRVALMITAVWVLAFAVSCPLLFGFNTTGDPTVCSISNPDFVIYSSVVSFYLPFGVTVLVYARIYVVLKQRRRKRILTRQNSQCNSVRPGFPQQTLSPDPAHLELKRYYSICQDTALGGPGFQERGGELKREEKTRNSLSPTIAPKLSLEVRKLSNGRLSTSLKLGPLQPRGVPLREKKATQMVAIVLGAFIVCWLPFFLTHVLNTHCQTCHVSPELYSATTWLGYVNSALNPVIYTTFNIEFRKAFLKILSC
  
Inhibitor
Name:
BDBM301790
Synonyms:
N-(4-(4-(2,3-Dichlorophenyl)piperazin-1-yl)butyl)-4-phenylpiperazine-1-carboxamide | US9598387, Compound 3 | US9969743, 3
Type:
Small organic molecule
Emp. Form.:
C25H33Cl2N5O
Mol. Mass.:
490.468
SMILES:
Clc1cccc(N2CCN(CCCCNC(=O)N3CCN(CC3)c3ccccc3)CC2)c1Cl
Structure:
Search PDB for entries with ligand similarity: