Reaction Details Report a problem with these data
Target
Cannabinoid receptor 1
Ligand
BDBM395822
Substrate
n/a
Meas. Tech.
Radioligand Binding Assay
EC50
>10000±n/a nM
Citation
 Gavelle, O; Grether, U; Kimbara, A; Nettekoven, M; Stephan, R; Rogers-Evans, M; Rombach, D; Schulz-Gasch, T Pyridine derivatives US Patent  US10308659 Publication Date 6/4/2019 
Target
Name:
Cannabinoid receptor 1
Synonyms:
CANN6 | CANNABINOID CB1 | CB-R | CB1 | CNR | CNR1 | CNR1_HUMAN | Cannabinoid CB1 receptor | Cannabinoid receptor | Cannabinoid receptor 1 (CB1) | Cannabinoid receptor 1 (brain)
Type:
G Protein-Coupled Receptor (GPCR)
Mol. Mass.:
52868.96
Organism:
Homo sapiens (Human)
Description:
P21554
Residue:
472
Sequence:
MKSILDGLADTTFRTITTDLLYVGSNDIQYEDIKGDMASKLGYFPQKFPLTSFRGSPFQEKMTAGDNPQLVPADQVNITEFYNKSLSSFKENEENIQCGENFMDIECFMVLNPSQQLAIAVLSLTLGTFTVLENLLVLCVILHSRSLRCRPSYHFIGSLAVADLLGSVIFVYSFIDFHVFHRKDSRNVFLFKLGGVTASFTASVGSLFLTAIDRYISIHRPLAYKRIVTRPKAVVAFCLMWTIAIVIAVLPLLGWNCEKLQSVCSDIFPHIDETYLMFWIGVTSVLLLFIVYAYMYILWKAHSHAVRMIQRGTQKSIIIHTSEDGKVQVTRPDQARMDIRLAKTLVLILVVLIICWGPLLAIMVYDVFGKMNKLIKTVFAFCSMLCLLNSTVNPIIYALRSKDLRHAFRSMFPSCEGTAQPLDNSMGDSDCLHKHANNAASVHRAAESCIKSTVKIAKVTMSVSTDTSAEAL
  
Inhibitor
Name:
BDBM395822
Synonyms:
2-[5-cyclopropyl-4-(cyclopropylmethoxy)pyridin-2-yl]-4-ethyl-4,5-dihydro-1,3-oxazole | US10308659, Example 21
Type:
Small organic molecule
Emp. Form.:
C17H22N2O2
Mol. Mass.:
286.3688
SMILES:
CCC1COC(=N1)c1cc(OCC2CC2)c(cn1)C1CC1 |c:5|
Structure:
Search PDB for entries with ligand similarity: