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TargetNADH dehydrogenase [ubiquinone] flavoprotein 1, mitochondrial
LigandBDBM263615
Substrate/Competitorn/a
Meas. Tech.Submitochondrial Particle Assay
pH7.4±n/a
IC50>1000±n/a nM
Commentsextracted
Citation Cesati, RRRadeke, HSPandey, SKPurohit, ARobinson, SP Compositions, methods, and systems for the synthesis and use of imaging agents US Patent US9713651 Publication Date 7/25/2017
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NADH dehydrogenase [ubiquinone] flavoprotein 1, mitochondrial
Name:NADH dehydrogenase [ubiquinone] flavoprotein 1, mitochondrial
Synonyms:CI-51kD | Complex I-51kD | NADH dehydrogenase flavoprotein 1 | NADH-ubiquinone oxidoreductase 51 kDa subunit | NDUFV1 | UQOR1
Type:PROTEIN
Mol. Mass.:50659.85
Organism:Bos taurus
Description:EBI_100771
Residue:464
Sequence:
MLAARRLLGGSLPARVSVRFSGDTTAPKKTSFGSLKDEDRIFTNLYGRHDWRLKGAQSRG
DWYKTKEILLKGPDWILGEVKTSGLRGRGGAGFPTGLKWSFMNKPSDGRPKYLVVNADEG
EPGTCKDREIIRHDPHKLVEGCLVGGRAMGARAAYIYIRGEFYNEASNLQVAIREAYEAG
LIGKNACGSGYDFDVFVVRGAGAYICGEETALIESIEGKQGKPRLKPPFPADVGVFGCPT
TVANVETVAVSPTICRRGGAWFASFGRERNSGTKLFNISGHVNNPCTVEEEMSVPLKELI
EKHAGGVTGGWDNLLAVIPGGSSTPLIPKSVCETVLMDFDALIQAQTGLGTAAVIVMDRS
TDIVKAIARLIEFYKHESCGQCTPCREGVDWMNKVMARFVRGDARPAEIDSLWEISKQIE
GHTICALGDGAAWPVQGLIRHFRPELEERMQQFAQQHQARQAAF
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BDBM263615
NameBDBM263615
Synonyms:2-(tert-butyl)-5-((4-((2-fluoroethoxy)methyl)benzyl)oxy)pyridazin-3(2H)-one | US9713651, 6
TypeSmall organic molecule
Emp. Form.C18H23FN2O3
Mol. Mass.334.3852
SMILESCC(C)(C)n1ncc(OCc2ccc(COCCF)cc2)cc1=O
Structure
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n/a