Target

Ligand

Substrate

Meas. Tech.

Dose Response Assay for Agonists of 5-Hydroxytryptamine (Serotonin) Receptor Subtype 1A (5HT1A)

pH

7.4±n/a

Temperature

296.15±n/a K

Citation

 PubChem, PC Dose Response Assay for 5-Hydroxytryptamine (Serotonin) Receptor Subtype 1a (5HT1a) Agonists PubChem Bioassay (2007)[AID] Copy BDB DOI

More Info.:

Get all data from this article,   Solution Info,  Assay Method

Name:

5-hydroxytryptamine receptor 1A

Synonyms:

5-HT-1A | 5-HT1A | 5-hydroxytryptamine receptor 1A (5-HT-1A) | 5HT1A_HUMAN | ADRB2RL1 | ADRBRL1 | Dopamine D2 receptor and serotonin 1a receptor | G-21 | HTR1A | Serotonin receptor 1A

Type:

n/a

Mol. Mass.:

46122.49

Organism:

Homo sapiens (Human)

Description:

n/a

Residue:

422

Sequence:

MDVLSPGQGNNTTSPPAPFETGGNTTGISDVTVSYQVITSLLLGTLIFCAVLGNACVVAAIALERSLQNVANYLIGSLAVTDLMVSVLVLPMAALYQVLNKWTLGQVTCDLFIALDVLCCTSSILHLCAIALDRYWAITDPIDYVNKRTPRRAAALISLTWLIGFLISIPPMLGWRTPEDRSDPDACTISKDHGYTIYSTFGAFYIPLLLMLVLYGRIFRAARFRIRKTVKKVEKTGADTRHGASPAPQPKKSVNGESGSRNWRLGVESKAGGALCANGAVRQGDDGAALEVIEVHRVGNSKEHLPLPSEAGPTPCAPASFERKNERNAEAKRKMALARERKTVKTLGIIMGTFILCWLPFFIVALVLPFCESSCHMPTLLGAIINWLGYSNSLLNPVIYAYFNKDFQNAFKKIIKCKFCRQ

Blast this sequence in BindingDB or PDB

  
Blast E-value cutoff:

Name:

BDBM30694

Synonyms:

(5,6-Dimethyl-4-oxo-4H-thieno[2,3-d]pyrimidin-3-yl)-acetic acid 1-tert-butylcarbamoyl-ethyl ester | 2-(4-keto-5,6-dimethyl-thieno[2,3-d]pyrimidin-3-yl)acetic acid [2-(tert-butylamino)-2-keto-1-methyl-ethyl] ester | 2-(5,6-dimethyl-4-oxo-3-thieno[2,3-d]pyrimidinyl)acetic acid [1-(tert-butylamino)-1-oxopropan-2-yl] ester | MLS000074979 | SMR000000460 | [1-(tert-butylamino)-1-oxidanylidene-propan-2-yl] 2-(5,6-dimethyl-4-oxidanylidene-thieno[2,3-d]pyrimidin-3-yl)ethanoate | [1-(tert-butylamino)-1-oxopropan-2-yl] 2-(5,6-dimethyl-4-oxothieno[2,3-d]pyrimidin-3-yl)acetate | cid_654522

Type:

Small organic molecule

Emp. Form.:

C17H23N3O4S

Mol. Mass.:

365.447

SMILES:

CC(OC(=O)Cn1cnc2sc(C)c(C)c2c1=O)C(=O)NC(C)(C)C

Structure:

Search PDB for entries with ligand similarity:

Similarity to this molecule at least:

Name:

Not Available

Synonyms:

n/a

Type:

n/a

Mol. Mass.:

358.43

Organism:

n/a

Description:

n/a

Residue:

3

Sequence:

NA