Reaction Details Report a problem with these data
Target
5-hydroxytryptamine receptor 1A
Ligand
BDBM30698
Substrate
Not Available
Meas. Tech.
Dose Response Assay for Agonists of 5-Hydroxytryptamine (Serotonin) Receptor Subtype 1A (5HT1A)
pH
7.4±n/a
Temperature
296.15±n/a K
EC50
99000±n/a nM
Citation
 PubChem, PC Dose Response Assay for 5-Hydroxytryptamine (Serotonin) Receptor Subtype 1a (5HT1a) Agonists PubChem Bioassay (2007)[AID] 
Target
Name:
5-hydroxytryptamine receptor 1A
Synonyms:
5-HT-1A | 5-HT1A | 5-hydroxytryptamine receptor 1A (5-HT-1A) | 5HT1A_HUMAN | ADRB2RL1 | ADRBRL1 | Dopamine D2 receptor and serotonin 1a receptor | G-21 | HTR1A | Serotonin receptor 1A
Type:
n/a
Mol. Mass.:
46122.49
Organism:
Homo sapiens (Human)
Description:
n/a
Residue:
422
Sequence:
MDVLSPGQGNNTTSPPAPFETGGNTTGISDVTVSYQVITSLLLGTLIFCAVLGNACVVAAIALERSLQNVANYLIGSLAVTDLMVSVLVLPMAALYQVLNKWTLGQVTCDLFIALDVLCCTSSILHLCAIALDRYWAITDPIDYVNKRTPRRAAALISLTWLIGFLISIPPMLGWRTPEDRSDPDACTISKDHGYTIYSTFGAFYIPLLLMLVLYGRIFRAARFRIRKTVKKVEKTGADTRHGASPAPQPKKSVNGESGSRNWRLGVESKAGGALCANGAVRQGDDGAALEVIEVHRVGNSKEHLPLPSEAGPTPCAPASFERKNERNAEAKRKMALARERKTVKTLGIIMGTFILCWLPFFIVALVLPFCESSCHMPTLLGAIINWLGYSNSLLNPVIYAYFNKDFQNAFKKIIKCKFCRQ
  
Inhibitor
Name:
BDBM30698
Synonyms:
2-(2,4-dimethoxyanilino)-7-keto-N-(tetrahydrofurfuryl)chromene-3-carboxamide | 2-(2,4-dimethoxyanilino)-7-oxo-N-(2-oxolanylmethyl)-1-benzopyran-3-carboxamide | 2-(2,4-dimethoxyanilino)-7-oxo-N-(oxolan-2-ylmethyl)chromene-3-carboxamide | 2-[(2,4-dimethoxyphenyl)amino]-7-oxidanylidene-N-(oxolan-2-ylmethyl)chromene-3-carboxamide | 2-[(Z)-2,4-Dimethoxy-phenylimino]-7-hydroxy-2H-chromene-3-carboxylic acid (tetrahydro-furan-2-ylmethyl)-amide | MLS000072508 | SMR000002220 | cid_656123
Type:
Small organic molecule
Emp. Form.:
C23H24N2O6
Mol. Mass.:
424.4465
SMILES:
COc1ccc(Nc2oc3cc(=O)ccc3cc2C(=O)NCC2CCCO2)c(OC)c1
Structure:
Search PDB for entries with ligand similarity:
Substrate
Name:
Not Available
Synonyms:
n/a
Type:
n/a
Mol. Mass.:
358.43
Organism:
n/a
Description:
n/a
Residue:
3
Sequence:
NA