Reaction Details Report a problem with these data
Target
5-hydroxytryptamine receptor 1A
Ligand
BDBM30871
Substrate
Not Available
Meas. Tech.
Dose Response Assay for Agonists of 5-Hydroxytryptamine (Serotonin) Receptor Subtype 1A (5HT1A)
pH
7.4±n/a
Temperature
296.15±n/a K
EC50
99000±n/a nM
Citation
 PubChem, PC Dose Response Assay for 5-Hydroxytryptamine (Serotonin) Receptor Subtype 1a (5HT1a) Agonists PubChem Bioassay (2007)[AID] 
Target
Name:
5-hydroxytryptamine receptor 1A
Synonyms:
5-HT-1A | 5-HT1A | 5-hydroxytryptamine receptor 1A (5-HT-1A) | 5HT1A_HUMAN | ADRB2RL1 | ADRBRL1 | Dopamine D2 receptor and serotonin 1a receptor | G-21 | HTR1A | Serotonin receptor 1A
Type:
n/a
Mol. Mass.:
46122.49
Organism:
Homo sapiens (Human)
Description:
n/a
Residue:
422
Sequence:
MDVLSPGQGNNTTSPPAPFETGGNTTGISDVTVSYQVITSLLLGTLIFCAVLGNACVVAAIALERSLQNVANYLIGSLAVTDLMVSVLVLPMAALYQVLNKWTLGQVTCDLFIALDVLCCTSSILHLCAIALDRYWAITDPIDYVNKRTPRRAAALISLTWLIGFLISIPPMLGWRTPEDRSDPDACTISKDHGYTIYSTFGAFYIPLLLMLVLYGRIFRAARFRIRKTVKKVEKTGADTRHGASPAPQPKKSVNGESGSRNWRLGVESKAGGALCANGAVRQGDDGAALEVIEVHRVGNSKEHLPLPSEAGPTPCAPASFERKNERNAEAKRKMALARERKTVKTLGIIMGTFILCWLPFFIVALVLPFCESSCHMPTLLGAIINWLGYSNSLLNPVIYAYFNKDFQNAFKKIIKCKFCRQ
  
Inhibitor
Name:
BDBM30871
Synonyms:
1,4-dioxa-8-azaspiro[4.5]decan-8-yl-[2-methyl-1-(3-methylphenyl)-5-benzimidazolyl]methanone | 1,4-dioxa-8-azaspiro[4.5]decan-8-yl-[2-methyl-1-(3-methylphenyl)benzimidazol-5-yl]methanone | 1,4-dioxa-8-azaspiro[4.5]decan-8-yl-[2-methyl-1-(m-tolyl)benzimidazol-5-yl]methanone | 8-{[2-methyl-1-(3-methylphenyl)-1H-benzimidazol-5-yl]carbonyl}-1,4-dioxa-8-azaspiro[4.5]decane | MLS000095931 | SMR000031479 | cid_3241342
Type:
Small organic molecule
Emp. Form.:
C23H25N3O3
Mol. Mass.:
391.4629
SMILES:
Cc1nc2cc(ccc2n1-c1cccc(C)c1)C(=O)N1CCC2(CC1)OCCO2
Structure:
Search PDB for entries with ligand similarity:
Substrate
Name:
Not Available
Synonyms:
n/a
Type:
n/a
Mol. Mass.:
358.43
Organism:
n/a
Description:
n/a
Residue:
3
Sequence:
NA