Reaction Details Report a problem with these data
Target
5-hydroxytryptamine receptor 1E
Ligand
BDBM31004
Substrate
Not Available
Meas. Tech.
Dose Response Cell Based High Throughput Screening Assay for Agonists of the 5-Hydroxytryptamine Receptor Subtype 1E (5HT1E)
pH
7.4±n/a
Temperature
296.15±n/a K
EC50
50000±n/a nM
Citation
 PubChem, PC Dose Response Cell Based High Throughput Screening Assay for Agonists of the 5-Hydroxytryptamine Receptor Subtype 1E (5HT1E) PubChem Bioassay (2007)[AID] 
Target
Name:
5-hydroxytryptamine receptor 1E
Synonyms:
5-HT-1E | 5-HT1E | 5-Hydroxytryptamine Receptor Subtype 1E (5HT1E) | 5-hydroxytryptamine receptor 1E | 5-hydroxytryptamine receptor 1E (5-HT-1E) (S31) | 5-hydroxytryptamine receptor 1E (5-HT-1E) (Serotonin receptor 1E) (5-HT1E) (S31). | 5HT1E_HUMAN | HTR1E | S31 | Serotonin (5-HT) receptor | Serotonin 1e (5-HT1e) receptor | Serotonin Receptor 1E
Type:
G Protein-Coupled Receptor (GPCR)
Mol. Mass.:
41697.80
Organism:
Homo sapiens (Human)
Description:
gi_112822
Residue:
365
Sequence:
MNITNCTTEASMAIRPKTITEKMLICMTLVVITTLTTLLNLAVIMAIGTTKKLHQPANYLICSLAVTDLLVAVLVMPLSIIYIVMDRWKLGYFLCEVWLSVDMTCCTCSILHLCVIALDRYWAITNAIEYARKRTAKRAALMILTVWTISIFISMPPLFWRSHRRLSPPPSQCTIQHDHVIYTIYSTLGAFYIPLTLILILYYRIYHAAKSLYQKRGSSRHLSNRSTDSQNSFASCKLTQTFCVSDFSTSDPTTEFEKFHASIRIPPFDNDLDHPGERQQISSTRERKAARILGLILGAFILSWLPFFIKELIVGLSIYTVSSEVADFLTWLGYVNSLINPLLYTSFNEDFKLAFKKLIRCREHT
  
Inhibitor
Name:
BDBM31004
Synonyms:
MLS000030962 | N-Cyclopentylcarbamoylmethyl-N-(3,4-dimethoxy-phenyl)-2-(5-p-tolyl-tetrazol-2-yl)-acetamide | N-[2-(cyclopentylamino)-2-keto-ethyl]-N-(3,4-dimethoxyphenyl)-2-[5-(p-tolyl)tetrazol-2-yl]acetamide | N-[2-(cyclopentylamino)-2-oxidanylidene-ethyl]-N-(3,4-dimethoxyphenyl)-2-[5-(4-methylphenyl)-1,2,3,4-tetrazol-2-yl]ethanamide | N-[2-(cyclopentylamino)-2-oxoethyl]-N-(3,4-dimethoxyphenyl)-2-[5-(4-methylphenyl)-2-tetrazolyl]acetamide | N-[2-(cyclopentylamino)-2-oxoethyl]-N-(3,4-dimethoxyphenyl)-2-[5-(4-methylphenyl)tetrazol-2-yl]acetamide | SMR000002705 | cid_655193
Type:
Small organic molecule
Emp. Form.:
C25H30N6O4
Mol. Mass.:
478.5435
SMILES:
COc1ccc(cc1OC)N(CC(=O)NC1CCCC1)C(=O)Cn1nnc(n1)-c1ccc(C)cc1
Structure:
Search PDB for entries with ligand similarity:
Substrate
Name:
Not Available
Synonyms:
n/a
Type:
n/a
Mol. Mass.:
358.43
Organism:
n/a
Description:
n/a
Residue:
3
Sequence:
NA