Target

Ligand

Substrate

Meas. Tech.

Fluorescence Resonance Energy Transfer (FRET) Assay

pH

7.5±n/a

Temperature

298.15±n/a K

Citation

 Suree, N; Yi, SW; Thieu, W; Marohn, M; Damoiseaux, R; Chan, A; Jung, ME; Clubb, RT Discovery and structure-activity relationship analysis of Staphylococcus aureus sortase A inhibitors. Bioorg Med Chem 17:7174-85 (2009) [PubMed]  Article Copy BDB DOI

More Info.:

Get all data from this article,  Inhibition_Run data,   Solution Info,  Assay Method

Name:

Sortase A

Synonyms:

LPXTG-site transpeptidase family protein | SRTA_BACAN | Sortase A (SrtA) | srtA

Type:

Enzyme

Mol. Mass.:

23150.63

Organism:

Bacillus anthracis

Description:

A0A0E0VVI0

Residue:

210

Sequence:

MNKQRIYSIVAILLFVVGGVLIGKPFYDGYQAEKKQTENVQAVQKMDYEKHETEFVDASKIDQPDLAEVANASLDKKQVIGRISIPSVSLELPVLKSSTEKNLLSGAATVKENQVMGKGNYALAGHNMSKKGVLFSDIASLKKGDKIYLYDNENEYEYAVTGVSEVTPDKWEVVEDHGKDEITLITCVSVKDNSKRYVVAGDLVGTKAKK

Blast this sequence in BindingDB or PDB

  
Blast E-value cutoff:

Name:

BDBM33311

Synonyms:

rhodanine, 1-12

Type:

Small organic molecule

Emp. Form.:

C16H12N2O4S2

Mol. Mass.:

360.407

SMILES:

CCN1C(=S)S\C(=C/c2ccc(o2)-c2ccccc2[N+]([O-])=O)C1=O

Structure:

Search PDB for entries with ligand similarity:

Similarity to this molecule at least:

Name:

BDBM33299

Synonyms:

Abz-LPETG-Dap(Dnp) | o-aminobenzoyl (Abz)-LPETG-diaminopropionic acid-dinitrophenyl- NH2

Type:

internally quenched fluorescent substrate

Emp. Form.:

n/a

Mol. Mass.:

n/a

SMILES:

n/a

Structure: