Target

Ligand

Substrate

Meas. Tech.

HTS discovery of chemical inhibitors of anti-apoptotic protein Bfl-1

pH

7±n/a

Temperature

296.15±n/a K

Citation

 PubChem, PC HTS discovery of chemical inhibitors of anti-apoptotic protein Bfl-1 PubChem Bioassay (2008)[AID] Copy BDB DOI

More Info.:

Get all data from this article,   Solution Info,  Assay Method

Name:

Bcl-2-related protein A1

Synonyms:

A1 | A1-A | B-cell leukemia/lymphoma 2 related protein A1a | B2LA1_MOUSE | Bcl2a1 | Bcl2a1a | Bfl-1 | Bfl1 | Hemopoietic-specific early response protein | Protein BFL-1

Type:

Apoptosis regulator protein

Mol. Mass.:

19909.74

Organism:

Mus musculus (Mouse)

Description:

gi_11024684

Residue:

172

Sequence:

MAESELMHIHSLAEHYLQYVLQVPAFESAPSQACRVLQRVAFSVQKEVEKNLKSYLDDFHVESIDTARIIFNQVMEKEFEDGIINWGRIVTIFAFGGVLLKKLPQEQIALDVCAYKQVSSFVAEFIMNNTGEWIRQNGGWEDGFIKKFEPKSGWLTFLQMTGQIWEMLFLLK

Blast this sequence in BindingDB or PDB

  
Blast E-value cutoff:

Name:

BDBM34182

Synonyms:

3-anilino-2H-isoquinolin-1-one | 3-anilinoisocarbostyril | 3-anilinoisoquinolin-1(2H)-one | 3-phenylazanyl-2H-isoquinolin-1-one | MLS000043701 | SMR000020713 | cid_2142225

Type:

Small organic molecule

Emp. Form.:

C15H12N2O

Mol. Mass.:

236.2686

SMILES:

O=c1[nH]c(Nc2ccccc2)cc2ccccc12

Structure:

Search PDB for entries with ligand similarity:

Similarity to this molecule at least:

Name:

FITC-Ahx-EDIIRNIARHLAQVGDSMDR

Synonyms:

FITC-Bid peptide

Type:

fluorescein-labeled peptide

Mol. Mass.:

358.43

Organism:

n/a

Description:

n/a

Residue:

3

Sequence:

NA