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Target
Cyclin-dependent kinase 16
Ligand
BDBM5931
Substrate
n/a
Meas. Tech.
Kinase Inhibitor Selectivity Profiling Assay
Kd
7.1±n/a nM
Citation
 PubChem, PC Kinase Inhibitor Selectivity Profiling Assay PubChem Bioassay (2008)[AID] 
Target
Name:
Cyclin-dependent kinase 16
Synonyms:
CDK16 | CDK16_HUMAN | PCTAIRE1 | PCTK1 | Serine/threonine-protein kinase PCTAIRE-1
Type:
Protein
Mol. Mass.:
55721.58
Organism:
Homo sapiens (Human)
Description:
Q00536
Residue:
496
Sequence:
MDRMKKIKRQLSMTLRGGRGIDKTNGAPEQIGLDESGGGGGSDPGEAPTRAAPGELRSARGPLSSAPEIVHEDLKMGSDGESDQASATSSDEVQSPVRVRMRNHPPRKISTEDINKRLSLPADIRLPEGYLEKLTLNSPIFDKPLSRRLRRVSLSEIGFGKLETYIKLDKLGEGTYATVYKGKSKLTDNLVALKEIRLEHEEGAPCTAIREVSLLKDLKHANIVTLHDIIHTEKSLTLVFEYLDKDLKQYLDDCGNIINMHNVKLFLFQLLRGLAYCHRQKVLHRDLKPQNLLINERGELKLADFGLARAKSIPTKTYSNEVVTLWYRPPDILLGSTDYSTQIDMWGVGCIFYEMATGRPLFPGSTVEEQLHFIFRILGTPTEETWPGILSNEEFKTYNYPKYRAEALLSHAPRLDSDGADLLTKLLQFEGRNRISAEDAMKHPFFLSLGERIHKLPDTTSIFALKEIQLQKEASLRSSSMPDSGRPAFRVVDTEF
  
Inhibitor
Name:
BDBM5931
Synonyms:
BMS-387072 | CHEMBL296468 | N-(5-{[(5-tert-butyl-1,3-oxazol-2-yl)methyl]sulfanyl}-1,3-thiazol-2-yl)piperidine-4-carboxamide | N-[5-[[[5-(1,1-Dimethylethyl)-2-oxazolyl]methyl]thio]-2-thiazolyl]-4-piperidinecarboxamide | cid_3025986
Type:
Small organic molecule
Emp. Form.:
C17H24N4O2S2
Mol. Mass.:
380.528
SMILES:
CC(C)(C)c1cnc(CSc2cnc(NC(=O)C3CCNCC3)s2)o1
Structure:
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