Reaction Details Report a problem with these data
Target
Sphingosine 1-phosphate receptor 3
Ligand
BDBM30729
Substrate
n/a
Meas. Tech.
S1P3 Agonist Dose-Response Potency Assay
EC50
178000±n/a nM
Citation
 PubChem, PC S1P3 Agonist Dose-Response Potency Assay PubChem Bioassay (2007)[AID] 
Target
Name:
Sphingosine 1-phosphate receptor 3
Synonyms:
C9orf108 | C9orf47 | EDG3 | Endothelial differentiation G-protein coupled receptor 3 | S1P receptor 3 | S1P receptor Edg-3 | S1P3 | S1PR3 | S1PR3_HUMAN | Sphingosine 1-phosphate receptor | Sphingosine 1-phosphate receptor 3 (S1P3) | Sphingosine 1-phosphate receptor Edg-3
Type:
G Protein-Coupled Receptor (GPCR)
Mol. Mass.:
42278.13
Organism:
Homo sapiens (Human)
Description:
Q99500
Residue:
378
Sequence:
MATALPPRLQPVRGNETLREHYQYVGKLAGRLKEASEGSTLTTVLFLVICSFIVLENLMVLIAIWKNNKFHNRMYFFIGNLALCDLLAGIAYKVNILMSGKKTFSLSPTVWFLREGSMFVALGASTCSLLAIAIERHLTMIKMRPYDANKRHRVFLLIGMCWLIAFTLGALPILGWNCLHNLPDCSTILPLYSKKYIAFCISIFTAILVTIVILYARIYFLVKSSSRKVANHNNSERSMALLRTVVIVVSVFIACWSPLFILFLIDVACRVQACPILFKAQWFIVLAVLNSAMNPVIYTLASKEMRRAFFRLVCNCLVRGRGARASPIQPALDPSRSKSSSSNNSSHSPKVKEDLPHTAPSSCIMDKNAALQNGIFCN
  
Inhibitor
Name:
BDBM30729
Synonyms:
2-amino-N-(2-morpholin-4-ylethyl)-1-(2-phenylethyl)pyrrolo[3,2-b]quinoxaline-3-carboxamide | 2-amino-N-(2-morpholinoethyl)-1-phenethyl-pyrrolo[3,2-b]quinoxaline-3-carboxamide | 2-amino-N-[2-(4-morpholinyl)ethyl]-1-(2-phenylethyl)-3-pyrrolo[3,2-b]quinoxalinecarboxamide | 2-azanyl-N-(2-morpholin-4-ylethyl)-1-(2-phenylethyl)pyrrolo[3,2-b]quinoxaline-3-carboxamide | MLS000079901 | SMR000040065 | cid_659090
Type:
Small organic molecule
Emp. Form.:
C25H28N6O2
Mol. Mass.:
444.5288
SMILES:
Nc1c(C(=O)NCCN2CCOCC2)c2nc3ccccc3nc2n1CCc1ccccc1
Structure:
Search PDB for entries with ligand similarity: