Reaction Details Report a problem with these data
Target
Sphingosine 1-phosphate receptor 3
Ligand
BDBM30771
Substrate
n/a
Meas. Tech.
S1P3 Agonist Dose-Response Potency Assay
EC50
19100±n/a nM
Citation
 PubChem, PC S1P3 Agonist Dose-Response Potency Assay PubChem Bioassay (2007)[AID] 
Target
Name:
Sphingosine 1-phosphate receptor 3
Synonyms:
C9orf108 | C9orf47 | EDG3 | Endothelial differentiation G-protein coupled receptor 3 | S1P receptor 3 | S1P receptor Edg-3 | S1P3 | S1PR3 | S1PR3_HUMAN | Sphingosine 1-phosphate receptor | Sphingosine 1-phosphate receptor 3 (S1P3) | Sphingosine 1-phosphate receptor Edg-3
Type:
G Protein-Coupled Receptor (GPCR)
Mol. Mass.:
42278.13
Organism:
Homo sapiens (Human)
Description:
Q99500
Residue:
378
Sequence:
MATALPPRLQPVRGNETLREHYQYVGKLAGRLKEASEGSTLTTVLFLVICSFIVLENLMVLIAIWKNNKFHNRMYFFIGNLALCDLLAGIAYKVNILMSGKKTFSLSPTVWFLREGSMFVALGASTCSLLAIAIERHLTMIKMRPYDANKRHRVFLLIGMCWLIAFTLGALPILGWNCLHNLPDCSTILPLYSKKYIAFCISIFTAILVTIVILYARIYFLVKSSSRKVANHNNSERSMALLRTVVIVVSVFIACWSPLFILFLIDVACRVQACPILFKAQWFIVLAVLNSAMNPVIYTLASKEMRRAFFRLVCNCLVRGRGARASPIQPALDPSRSKSSSSNNSSHSPKVKEDLPHTAPSSCIMDKNAALQNGIFCN
  
Inhibitor
Name:
BDBM30771
Synonyms:
2-amino-1-(3-morpholinopropyl)-N-piperonyl-pyrrolo[3,2-b]quinoxaline-3-carboxamide | 2-amino-N-(1,3-benzodioxol-5-ylmethyl)-1-(3-morpholin-4-ylpropyl)pyrrolo[3,2-b]quinoxaline-3-carboxamide | 2-amino-N-(1,3-benzodioxol-5-ylmethyl)-1-[3-(4-morpholinyl)propyl]-3-pyrrolo[3,2-b]quinoxalinecarboxamide | 2-azanyl-N-(1,3-benzodioxol-5-ylmethyl)-1-(3-morpholin-4-ylpropyl)pyrrolo[3,2-b]quinoxaline-3-carboxamide | MLS000040782 | SMR000044765 | cid_663945
Type:
Small organic molecule
Emp. Form.:
C26H28N6O4
Mol. Mass.:
488.5383
SMILES:
Nc1c(C(=O)NCc2ccc3OCOc3c2)c2nc3ccccc3nc2n1CCCN1CCOCC1
Structure:
Search PDB for entries with ligand similarity: