Reaction Details Report a problem with these data
Target
Sphingosine 1-phosphate receptor 3
Ligand
BDBM30831
Substrate
n/a
Meas. Tech.
S1P3 Agonist Dose-Response Potency Assay
EC50
>45000±n/a nM
Citation
 PubChem, PC S1P3 Agonist Dose-Response Potency Assay PubChem Bioassay (2007)[AID] 
Target
Name:
Sphingosine 1-phosphate receptor 3
Synonyms:
C9orf108 | C9orf47 | EDG3 | Endothelial differentiation G-protein coupled receptor 3 | S1P receptor 3 | S1P receptor Edg-3 | S1P3 | S1PR3 | S1PR3_HUMAN | Sphingosine 1-phosphate receptor | Sphingosine 1-phosphate receptor 3 (S1P3) | Sphingosine 1-phosphate receptor Edg-3
Type:
G Protein-Coupled Receptor (GPCR)
Mol. Mass.:
42278.13
Organism:
Homo sapiens (Human)
Description:
Q99500
Residue:
378
Sequence:
MATALPPRLQPVRGNETLREHYQYVGKLAGRLKEASEGSTLTTVLFLVICSFIVLENLMVLIAIWKNNKFHNRMYFFIGNLALCDLLAGIAYKVNILMSGKKTFSLSPTVWFLREGSMFVALGASTCSLLAIAIERHLTMIKMRPYDANKRHRVFLLIGMCWLIAFTLGALPILGWNCLHNLPDCSTILPLYSKKYIAFCISIFTAILVTIVILYARIYFLVKSSSRKVANHNNSERSMALLRTVVIVVSVFIACWSPLFILFLIDVACRVQACPILFKAQWFIVLAVLNSAMNPVIYTLASKEMRRAFFRLVCNCLVRGRGARASPIQPALDPSRSKSSSSNNSSHSPKVKEDLPHTAPSSCIMDKNAALQNGIFCN
  
Inhibitor
Name:
BDBM30831
Synonyms:
MLS000055622 | N-(1-butyl-3-cyano-2-pyrrolo[3,2-b]quinoxalinyl)-4-fluorobenzamide | N-(1-butyl-3-cyano-pyrrolo[3,2-b]quinoxalin-2-yl)-4-fluoranyl-benzamide | N-(1-butyl-3-cyano-pyrrolo[3,2-b]quinoxalin-2-yl)-4-fluoro-benzamide | N-(1-butyl-3-cyanopyrrolo[3,2-b]quinoxalin-2-yl)-4-fluorobenzamide | SMR000060157 | US9045483, 13 | cid_2323827
Type:
Small organic molecule
Emp. Form.:
C22H18FN5O
Mol. Mass.:
387.4096
SMILES:
CCCCn1c(NC(=O)c2ccc(F)cc2)c(C#N)c2nc3ccccc3nc12
Structure:
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