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Target
Sphingosine 1-phosphate receptor 1
Ligand
BDBM36837
Substrate
n/a
Meas. Tech.
Dose Response Assays for S1P1 Agonists and Agonism Potentiators - Parental Cell Line Counter Screen 60K MLSMR
EC50
26000±n/a nM
Citation
 PubChem, PC Dose Response Assays for S1P1 Agonists and Agonism Potentiators - Parental Cell Line Counter Screen 60K MLSMR PubChem Bioassay (2007)[AID] 
Target
Name:
Sphingosine 1-phosphate receptor 1
Synonyms:
CHEDG1 | EDG1 | Endothelial differentiation G-protein coupled receptor 1 | S1P receptor | S1P1 | S1PR1 | S1PR1_HUMAN | Sphingosine 1-phosphate receptor 1 (S1PR1) | Sphingosine 1-phosphate receptor Edg-1
Type:
Enzyme
Mol. Mass.:
42836.02
Organism:
Homo sapiens (Human)
Description:
P21453
Residue:
382
Sequence:
MGPTSVPLVKAHRSSVSDYVNYDIIVRHYNYTGKLNISADKENSIKLTSVVFILICCFIILENIFVLLTIWKTKKFHRPMYYFIGNLALSDLLAGVAYTANLLLSGATTYKLTPAQWFLREGSMFVALSASVFSLLAIAIERYITMLKMKLHNGSNNFRLFLLISACWVISLILGGLPIMGWNCISALSSCSTVLPLYHKHYILFCTTVFTLLLLSIVILYCRIYSLVRTRSRRLTFRKNISKASRSSEKSLALLKTVIIVLSVFIACWAPLFILLLLDVGCKVKTCDILFRAEYFLVLAVLNSGTNPIIYTLTNKEMRRAFIRIMSCCKCPSGDSAGKFKRPIIAGMEFSRSKSDNSSHPQKDEGDNPETIMSSGNVNSSS
  
Inhibitor
Name:
BDBM36837
Synonyms:
MLS000034491 | N-[3-Chloro-4-(4-isobutyryl-piperazin-1-yl)-phenyl]-2-o-tolyloxy-acetamide | N-[3-chloranyl-4-[4-(2-methylpropanoyl)piperazin-1-yl]phenyl]-2-(2-methylphenoxy)ethanamide | N-[3-chloro-4-(4-isobutyrylpiperazino)phenyl]-2-(2-methylphenoxy)acetamide | N-[3-chloro-4-[4-(2-methyl-1-oxopropyl)-1-piperazinyl]phenyl]-2-(2-methylphenoxy)acetamide | N-[3-chloro-4-[4-(2-methylpropanoyl)piperazin-1-yl]phenyl]-2-(2-methylphenoxy)acetamide | SMR000014234 | cid_647748
Type:
Small organic molecule
Emp. Form.:
C23H28ClN3O3
Mol. Mass.:
429.94
SMILES:
CC(C)C(=O)N1CCN(CC1)c1ccc(NC(=O)COc2ccccc2C)cc1Cl
Structure:
Search PDB for entries with ligand similarity: