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Target
Sphingosine 1-phosphate receptor 1
Ligand
BDBM36860
Substrate
n/a
Meas. Tech.
Dose Response Assays for S1P1 Agonists and Agonism Potentiators - Parental Cell Line Counter Screen 60K MLSMR
EC50
>95100±n/a nM
Citation
 PubChem, PC Dose Response Assays for S1P1 Agonists and Agonism Potentiators - Parental Cell Line Counter Screen 60K MLSMR PubChem Bioassay (2007)[AID] 
Target
Name:
Sphingosine 1-phosphate receptor 1
Synonyms:
CHEDG1 | EDG1 | Endothelial differentiation G-protein coupled receptor 1 | S1P receptor | S1P1 | S1PR1 | S1PR1_HUMAN | Sphingosine 1-phosphate receptor 1 (S1PR1) | Sphingosine 1-phosphate receptor Edg-1
Type:
Enzyme
Mol. Mass.:
42836.02
Organism:
Homo sapiens (Human)
Description:
P21453
Residue:
382
Sequence:
MGPTSVPLVKAHRSSVSDYVNYDIIVRHYNYTGKLNISADKENSIKLTSVVFILICCFIILENIFVLLTIWKTKKFHRPMYYFIGNLALSDLLAGVAYTANLLLSGATTYKLTPAQWFLREGSMFVALSASVFSLLAIAIERYITMLKMKLHNGSNNFRLFLLISACWVISLILGGLPIMGWNCISALSSCSTVLPLYHKHYILFCTTVFTLLLLSIVILYCRIYSLVRTRSRRLTFRKNISKASRSSEKSLALLKTVIIVLSVFIACWAPLFILLLLDVGCKVKTCDILFRAEYFLVLAVLNSGTNPIIYTLTNKEMRRAFIRIMSCCKCPSGDSAGKFKRPIIAGMEFSRSKSDNSSHPQKDEGDNPETIMSSGNVNSSS
  
Inhibitor
Name:
BDBM36860
Synonyms:
5-Methyl-7-[4-((E)-3-phenyl-allyl)-piperazin-1-yl]-[1,2,4]triazolo[1,5-a]pyrimidine | 5-methyl-7-[4-[(E)-3-phenylprop-2-enyl]-1-piperazinyl]-[1,2,4]triazolo[1,5-a]pyrimidine | 5-methyl-7-[4-[(E)-3-phenylprop-2-enyl]piperazin-1-yl]-[1,2,4]triazolo[1,5-a]pyrimidine | 7-[4-[(E)-cinnamyl]piperazino]-5-methyl-[1,2,4]triazolo[1,5-a]pyrimidine | MLS000071091 | SMR000008092 | cid_5771238
Type:
Small organic molecule
Emp. Form.:
C19H22N6
Mol. Mass.:
334.4182
SMILES:
Cc1cc(N2CCN(C\C=C\c3ccccc3)CC2)n2ncnc2n1
Structure:
Search PDB for entries with ligand similarity: