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Target
Sphingosine 1-phosphate receptor 1
Ligand
BDBM36872
Substrate
n/a
Meas. Tech.
Dose Response Assays for S1P1 Agonists and Agonism Potentiators - Parental Cell Line Counter Screen 60K MLSMR
EC50
>95100±n/a nM
Citation
 PubChem, PC Dose Response Assays for S1P1 Agonists and Agonism Potentiators - Parental Cell Line Counter Screen 60K MLSMR PubChem Bioassay (2007)[AID] 
Target
Name:
Sphingosine 1-phosphate receptor 1
Synonyms:
CHEDG1 | EDG1 | Endothelial differentiation G-protein coupled receptor 1 | S1P receptor | S1P1 | S1PR1 | S1PR1_HUMAN | Sphingosine 1-phosphate receptor 1 (S1PR1) | Sphingosine 1-phosphate receptor Edg-1
Type:
Enzyme
Mol. Mass.:
42836.02
Organism:
Homo sapiens (Human)
Description:
P21453
Residue:
382
Sequence:
MGPTSVPLVKAHRSSVSDYVNYDIIVRHYNYTGKLNISADKENSIKLTSVVFILICCFIILENIFVLLTIWKTKKFHRPMYYFIGNLALSDLLAGVAYTANLLLSGATTYKLTPAQWFLREGSMFVALSASVFSLLAIAIERYITMLKMKLHNGSNNFRLFLLISACWVISLILGGLPIMGWNCISALSSCSTVLPLYHKHYILFCTTVFTLLLLSIVILYCRIYSLVRTRSRRLTFRKNISKASRSSEKSLALLKTVIIVLSVFIACWAPLFILLLLDVGCKVKTCDILFRAEYFLVLAVLNSGTNPIIYTLTNKEMRRAFIRIMSCCKCPSGDSAGKFKRPIIAGMEFSRSKSDNSSHPQKDEGDNPETIMSSGNVNSSS
  
Inhibitor
Name:
BDBM36872
Synonyms:
MLS000033292 | N'-[2-(cyclopentylamino)-2-keto-1-(4-pyridyl)ethyl]-N'-(2-furfuryl)-N-(3-pyridyl)succinamide | N'-[2-(cyclopentylamino)-2-oxidanylidene-1-pyridin-4-yl-ethyl]-N'-(furan-2-ylmethyl)-N-pyridin-3-yl-butanediamide | N'-[2-(cyclopentylamino)-2-oxo-1-pyridin-4-ylethyl]-N'-(2-furanylmethyl)-N-(3-pyridinyl)butanediamide | N'-[2-(cyclopentylamino)-2-oxo-1-pyridin-4-ylethyl]-N'-(furan-2-ylmethyl)-N-pyridin-3-ylbutanediamide | N-(Cyclopentylcarbamoyl-pyridin-4-yl-methyl)-N-furan-2-ylmethyl-N'-pyridin-3-yl-succinamide | SMR000006108 | cid_654946
Type:
Small organic molecule
Emp. Form.:
C26H29N5O4
Mol. Mass.:
475.5396
SMILES:
O=C(CCC(=O)N(Cc1ccco1)C(C(=O)NC1CCCC1)c1ccncc1)Nc1cccnc1
Structure:
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