Reaction Details Report a problem with these data
Target
Sphingosine 1-phosphate receptor 1
Ligand
BDBM36951
Substrate
n/a
Meas. Tech.
Dose Response Assays for S1P1 Agonists and Agonism Potentiators - Parental Cell Line Counter Screen 60K MLSMR
EC50
>30000±n/a nM
Citation
 PubChem, PC Dose Response Assays for S1P1 Agonists and Agonism Potentiators - Parental Cell Line Counter Screen 60K MLSMR PubChem Bioassay (2007)[AID] 
Target
Name:
Sphingosine 1-phosphate receptor 1
Synonyms:
CHEDG1 | EDG1 | Endothelial differentiation G-protein coupled receptor 1 | S1P receptor | S1P1 | S1PR1 | S1PR1_HUMAN | Sphingosine 1-phosphate receptor 1 (S1PR1) | Sphingosine 1-phosphate receptor Edg-1
Type:
Enzyme
Mol. Mass.:
42836.02
Organism:
Homo sapiens (Human)
Description:
P21453
Residue:
382
Sequence:
MGPTSVPLVKAHRSSVSDYVNYDIIVRHYNYTGKLNISADKENSIKLTSVVFILICCFIILENIFVLLTIWKTKKFHRPMYYFIGNLALSDLLAGVAYTANLLLSGATTYKLTPAQWFLREGSMFVALSASVFSLLAIAIERYITMLKMKLHNGSNNFRLFLLISACWVISLILGGLPIMGWNCISALSSCSTVLPLYHKHYILFCTTVFTLLLLSIVILYCRIYSLVRTRSRRLTFRKNISKASRSSEKSLALLKTVIIVLSVFIACWAPLFILLLLDVGCKVKTCDILFRAEYFLVLAVLNSGTNPIIYTLTNKEMRRAFIRIMSCCKCPSGDSAGKFKRPIIAGMEFSRSKSDNSSHPQKDEGDNPETIMSSGNVNSSS
  
Inhibitor
Name:
BDBM36951
Synonyms:
7-(4-benzhydrylpiperazin-1-yl)-5-methyl-[1,2,4]triazolo[1,5-a]pyrimidine | 7-(4-benzhydrylpiperazino)-5-methyl-[1,2,4]triazolo[1,5-a]pyrimidine | 7-[4-(diphenylmethyl)-1-piperazinyl]-5-methyl-[1,2,4]triazolo[1,5-a]pyrimidine | 7-[4-(diphenylmethyl)piperazin-1-yl]-5-methyl-[1,2,4]triazolo[1,5-a]pyrimidine | MLS000083709 | SMR000047410 | cid_666031
Type:
Small organic molecule
Emp. Form.:
C23H24N6
Mol. Mass.:
384.4769
SMILES:
Cc1cc(N2CCN(CC2)C(c2ccccc2)c2ccccc2)n2ncnc2n1
Structure:
Search PDB for entries with ligand similarity: