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Target
Sphingosine 1-phosphate receptor 1
Ligand
BDBM31066
Substrate
n/a
Meas. Tech.
Dose Response Assays for S1P1 Agonists and Agonism Potentiators - Parental Cell Line Counter Screen 60K MLSMR
EC50
1340±n/a nM
Citation
 PubChem, PC Dose Response Assays for S1P1 Agonists and Agonism Potentiators - Parental Cell Line Counter Screen 60K MLSMR PubChem Bioassay (2007)[AID] 
Target
Name:
Sphingosine 1-phosphate receptor 1
Synonyms:
CHEDG1 | EDG1 | Endothelial differentiation G-protein coupled receptor 1 | S1P receptor | S1P1 | S1PR1 | S1PR1_HUMAN | Sphingosine 1-phosphate receptor 1 (S1PR1) | Sphingosine 1-phosphate receptor Edg-1
Type:
Enzyme
Mol. Mass.:
42836.02
Organism:
Homo sapiens (Human)
Description:
P21453
Residue:
382
Sequence:
MGPTSVPLVKAHRSSVSDYVNYDIIVRHYNYTGKLNISADKENSIKLTSVVFILICCFIILENIFVLLTIWKTKKFHRPMYYFIGNLALSDLLAGVAYTANLLLSGATTYKLTPAQWFLREGSMFVALSASVFSLLAIAIERYITMLKMKLHNGSNNFRLFLLISACWVISLILGGLPIMGWNCISALSSCSTVLPLYHKHYILFCTTVFTLLLLSIVILYCRIYSLVRTRSRRLTFRKNISKASRSSEKSLALLKTVIIVLSVFIACWAPLFILLLLDVGCKVKTCDILFRAEYFLVLAVLNSGTNPIIYTLTNKEMRRAFIRIMSCCKCPSGDSAGKFKRPIIAGMEFSRSKSDNSSHPQKDEGDNPETIMSSGNVNSSS
  
Inhibitor
Name:
BDBM31066
Synonyms:
3-(1-phenyltetrazol-5-yl)sulfonylpropanenitrile | 3-(1-phenyltetrazol-5-yl)sulfonylpropionitrile | 3-[(1-phenyl-1,2,3,4-tetrazol-5-yl)sulfonyl]propanenitrile | 3-[(1-phenyl-1H-tetrazol-5-yl)sulfonyl]propanenitrile | 3-[(1-phenyl-5-tetrazolyl)sulfonyl]propanenitrile | MLS000085949 | SMR000021278 | cid_3242053
Type:
Small organic molecule
Emp. Form.:
C10H9N5O2S
Mol. Mass.:
263.276
SMILES:
O=S(=O)(CCC#N)c1nnnn1-c1ccccc1
Structure:
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