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Target
Sphingosine 1-phosphate receptor 1
Ligand
BDBM37156
Substrate
n/a
Meas. Tech.
Dose Response Assays for S1P1 Agonists and Agonism Potentiators - Parental Cell Line Counter Screen 60K MLSMR
EC50
>95100±n/a nM
Citation
 PubChem, PC Dose Response Assays for S1P1 Agonists and Agonism Potentiators - Parental Cell Line Counter Screen 60K MLSMR PubChem Bioassay (2007)[AID] 
Target
Name:
Sphingosine 1-phosphate receptor 1
Synonyms:
CHEDG1 | EDG1 | Endothelial differentiation G-protein coupled receptor 1 | S1P receptor | S1P1 | S1PR1 | S1PR1_HUMAN | Sphingosine 1-phosphate receptor 1 (S1PR1) | Sphingosine 1-phosphate receptor Edg-1
Type:
Enzyme
Mol. Mass.:
42836.02
Organism:
Homo sapiens (Human)
Description:
P21453
Residue:
382
Sequence:
MGPTSVPLVKAHRSSVSDYVNYDIIVRHYNYTGKLNISADKENSIKLTSVVFILICCFIILENIFVLLTIWKTKKFHRPMYYFIGNLALSDLLAGVAYTANLLLSGATTYKLTPAQWFLREGSMFVALSASVFSLLAIAIERYITMLKMKLHNGSNNFRLFLLISACWVISLILGGLPIMGWNCISALSSCSTVLPLYHKHYILFCTTVFTLLLLSIVILYCRIYSLVRTRSRRLTFRKNISKASRSSEKSLALLKTVIIVLSVFIACWAPLFILLLLDVGCKVKTCDILFRAEYFLVLAVLNSGTNPIIYTLTNKEMRRAFIRIMSCCKCPSGDSAGKFKRPIIAGMEFSRSKSDNSSHPQKDEGDNPETIMSSGNVNSSS
  
Inhibitor
Name:
BDBM37156
Synonyms:
3-[(4-chloranylpyrazol-1-yl)methyl]-N-(1-ethylbenzimidazol-2-yl)benzamide | 3-[(4-chloro-1-pyrazolyl)methyl]-N-(1-ethyl-2-benzimidazolyl)benzamide | 3-[(4-chloropyrazol-1-yl)methyl]-N-(1-ethylbenzimidazol-2-yl)benzamide | MLS000114624 | SMR000091975 | cid_5142655
Type:
Small organic molecule
Emp. Form.:
C20H18ClN5O
Mol. Mass.:
379.843
SMILES:
CCn1c(NC(=O)c2cccc(Cn3cc(Cl)cn3)c2)nc2ccccc12
Structure:
Search PDB for entries with ligand similarity: