Target
Sphingosine 1-phosphate receptor 1
Ligand
BDBM37037
Substrate
n/a
Meas. Tech.
Dose Response Assays for S1P1 Agonists and Agonism Potentiators - Agonist Assay 60K MLSMR
EC50
>30000±n/a nM
Citation
 PubChem, PC Dose Response Assays for S1P1 Agonists and Agonism Potentiators - Agonist Assay 60K MLSMR PubChem Bioassay (2007)[AID] 
Target
Name:
Sphingosine 1-phosphate receptor 1
Synonyms:
CHEDG1 | EDG1 | Endothelial differentiation G-protein coupled receptor 1 | S1P receptor | S1P1 | S1PR1 | S1PR1_HUMAN | Sphingosine 1-phosphate receptor 1 (S1PR1) | Sphingosine 1-phosphate receptor Edg-1
Type:
Enzyme
Mol. Mass.:
42836.02
Organism:
Homo sapiens (Human)
Description:
P21453
Residue:
382
Sequence:
MGPTSVPLVKAHRSSVSDYVNYDIIVRHYNYTGKLNISADKENSIKLTSVVFILICCFIILENIFVLLTIWKTKKFHRPMYYFIGNLALSDLLAGVAYTANLLLSGATTYKLTPAQWFLREGSMFVALSASVFSLLAIAIERYITMLKMKLHNGSNNFRLFLLISACWVISLILGGLPIMGWNCISALSSCSTVLPLYHKHYILFCTTVFTLLLLSIVILYCRIYSLVRTRSRRLTFRKNISKASRSSEKSLALLKTVIIVLSVFIACWAPLFILLLLDVGCKVKTCDILFRAEYFLVLAVLNSGTNPIIYTLTNKEMRRAFIRIMSCCKCPSGDSAGKFKRPIIAGMEFSRSKSDNSSHPQKDEGDNPETIMSSGNVNSSS
  
Inhibitor
Name:
BDBM37037
Synonyms:
2-(3,4-dihydroisoquinolin-2(1H)-ylcarbonyl)-1-methyl-1H-[1]benzofuro[3,2-b]pyrrole | 3,4-dihydro-1H-isoquinolin-2-yl-(1-methyl-2-benzofuro[3,2-b]pyrrolyl)methanone | 3,4-dihydro-1H-isoquinolin-2-yl-(1-methyl-[1]benzofuro[3,2-b]pyrrol-2-yl)methanone | 3,4-dihydro-1H-isoquinolin-2-yl-(1-methylbenzofuro[3,2-b]pyrrol-2-yl)methanone | MLS000093643 | SMR000029261 | cid_3236996
Type:
Small organic molecule
Emp. Form.:
C21H18N2O2
Mol. Mass.:
330.3798
SMILES:
Cn1c(cc2oc3ccccc3c12)C(=O)N1CCc2ccccc2C1
Structure:
Search PDB for entries with ligand similarity: