Reaction Details Report a problem with these data
Target
Sphingosine 1-phosphate receptor 3
Ligand
BDBM37354
Substrate
n/a
Meas. Tech.
Dose Response Assay for S1P3 Antagonists
IC50
>1840±n/a nM
Citation
 PubChem, PC Dose Response Assay for S1P3 Antagonists PubChem Bioassay (2007)[AID] 
Target
Name:
Sphingosine 1-phosphate receptor 3
Synonyms:
C9orf108 | C9orf47 | EDG3 | Endothelial differentiation G-protein coupled receptor 3 | S1P receptor 3 | S1P receptor Edg-3 | S1P3 | S1PR3 | S1PR3_HUMAN | Sphingosine 1-phosphate receptor | Sphingosine 1-phosphate receptor 3 (S1P3) | Sphingosine 1-phosphate receptor Edg-3
Type:
G Protein-Coupled Receptor (GPCR)
Mol. Mass.:
42278.13
Organism:
Homo sapiens (Human)
Description:
Q99500
Residue:
378
Sequence:
MATALPPRLQPVRGNETLREHYQYVGKLAGRLKEASEGSTLTTVLFLVICSFIVLENLMVLIAIWKNNKFHNRMYFFIGNLALCDLLAGIAYKVNILMSGKKTFSLSPTVWFLREGSMFVALGASTCSLLAIAIERHLTMIKMRPYDANKRHRVFLLIGMCWLIAFTLGALPILGWNCLHNLPDCSTILPLYSKKYIAFCISIFTAILVTIVILYARIYFLVKSSSRKVANHNNSERSMALLRTVVIVVSVFIACWSPLFILFLIDVACRVQACPILFKAQWFIVLAVLNSAMNPVIYTLASKEMRRAFFRLVCNCLVRGRGARASPIQPALDPSRSKSSSSNNSSHSPKVKEDLPHTAPSSCIMDKNAALQNGIFCN
  
Inhibitor
Name:
BDBM37354
Synonyms:
MLS000032033 | N-[2-[4-(4-fluorophenyl)-1-piperazinyl]phenyl]benzamide | N-[2-[4-(4-fluorophenyl)piperazin-1-yl]phenyl]benzamide | N-[2-[4-(4-fluorophenyl)piperazino]phenyl]benzamide | N-{2-[4-(4-Fluoro-phenyl)-piperazin-1-yl]-phenyl}-benzamide | SMR000005875 | cid_647282
Type:
Small organic molecule
Emp. Form.:
C23H22FN3O
Mol. Mass.:
375.4387
SMILES:
Fc1ccc(cc1)N1CCN(CC1)c1ccccc1NC(=O)c1ccccc1
Structure:
Search PDB for entries with ligand similarity: