Reaction Details Report a problem with these data
Target
Sphingosine 1-phosphate receptor 3
Ligand
BDBM37364
Substrate
n/a
Meas. Tech.
Dose Response Assay for S1P3 Antagonists
IC50
>16600±n/a nM
Citation
 PubChem, PC Dose Response Assay for S1P3 Antagonists PubChem Bioassay (2007)[AID] 
Target
Name:
Sphingosine 1-phosphate receptor 3
Synonyms:
C9orf108 | C9orf47 | EDG3 | Endothelial differentiation G-protein coupled receptor 3 | S1P receptor 3 | S1P receptor Edg-3 | S1P3 | S1PR3 | S1PR3_HUMAN | Sphingosine 1-phosphate receptor | Sphingosine 1-phosphate receptor 3 (S1P3) | Sphingosine 1-phosphate receptor Edg-3
Type:
G Protein-Coupled Receptor (GPCR)
Mol. Mass.:
42278.13
Organism:
Homo sapiens (Human)
Description:
Q99500
Residue:
378
Sequence:
MATALPPRLQPVRGNETLREHYQYVGKLAGRLKEASEGSTLTTVLFLVICSFIVLENLMVLIAIWKNNKFHNRMYFFIGNLALCDLLAGIAYKVNILMSGKKTFSLSPTVWFLREGSMFVALGASTCSLLAIAIERHLTMIKMRPYDANKRHRVFLLIGMCWLIAFTLGALPILGWNCLHNLPDCSTILPLYSKKYIAFCISIFTAILVTIVILYARIYFLVKSSSRKVANHNNSERSMALLRTVVIVVSVFIACWSPLFILFLIDVACRVQACPILFKAQWFIVLAVLNSAMNPVIYTLASKEMRRAFFRLVCNCLVRGRGARASPIQPALDPSRSKSSSSNNSSHSPKVKEDLPHTAPSSCIMDKNAALQNGIFCN
  
Inhibitor
Name:
BDBM37364
Synonyms:
(6-Methyl-3-oxo-2,3-dihydro-benzo[1,4]oxazin-4-yl)-acetic acid 1-cyclopentylcarbamoyl-3-methyl-butyl ester | 2-(3-keto-6-methyl-1,4-benzoxazin-4-yl)acetic acid [1-(cyclopentylcarbamoyl)-3-methyl-butyl] ester | 2-(6-methyl-3-oxo-1,4-benzoxazin-4-yl)acetic acid [1-(cyclopentylamino)-4-methyl-1-oxopentan-2-yl] ester | MLS000074427 | SMR000007793 | [1-(cyclopentylamino)-4-methyl-1-oxidanylidene-pentan-2-yl] 2-(6-methyl-3-oxidanylidene-1,4-benzoxazin-4-yl)ethanoate | [1-(cyclopentylamino)-4-methyl-1-oxopentan-2-yl] 2-(6-methyl-3-oxo-1,4-benzoxazin-4-yl)acetate | cid_651722
Type:
Small organic molecule
Emp. Form.:
C22H30N2O5
Mol. Mass.:
402.484
SMILES:
CC(C)CC(OC(=O)CN1C(=O)COc2ccc(C)cc12)C(=O)NC1CCCC1
Structure:
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