Reaction Details Report a problem with these data
Target
Sphingosine 1-phosphate receptor 3
Ligand
BDBM37426
Substrate
n/a
Meas. Tech.
Dose Response Assay for S1P3 Antagonists
IC50
39350±n/a nM
Citation
 PubChem, PC Dose Response Assay for S1P3 Antagonists PubChem Bioassay (2007)[AID] 
Target
Name:
Sphingosine 1-phosphate receptor 3
Synonyms:
C9orf108 | C9orf47 | EDG3 | Endothelial differentiation G-protein coupled receptor 3 | S1P receptor 3 | S1P receptor Edg-3 | S1P3 | S1PR3 | S1PR3_HUMAN | Sphingosine 1-phosphate receptor | Sphingosine 1-phosphate receptor 3 (S1P3) | Sphingosine 1-phosphate receptor Edg-3
Type:
G Protein-Coupled Receptor (GPCR)
Mol. Mass.:
42278.13
Organism:
Homo sapiens (Human)
Description:
Q99500
Residue:
378
Sequence:
MATALPPRLQPVRGNETLREHYQYVGKLAGRLKEASEGSTLTTVLFLVICSFIVLENLMVLIAIWKNNKFHNRMYFFIGNLALCDLLAGIAYKVNILMSGKKTFSLSPTVWFLREGSMFVALGASTCSLLAIAIERHLTMIKMRPYDANKRHRVFLLIGMCWLIAFTLGALPILGWNCLHNLPDCSTILPLYSKKYIAFCISIFTAILVTIVILYARIYFLVKSSSRKVANHNNSERSMALLRTVVIVVSVFIACWSPLFILFLIDVACRVQACPILFKAQWFIVLAVLNSAMNPVIYTLASKEMRRAFFRLVCNCLVRGRGARASPIQPALDPSRSKSSSSNNSSHSPKVKEDLPHTAPSSCIMDKNAALQNGIFCN
  
Inhibitor
Name:
BDBM37426
Synonyms:
3-amino-4-anilino-2-thieno[2,3-b]pyridinecarboxamide | 3-amino-4-anilino-thieno[2,3-b]pyridine-2-carboxamide | 3-amino-4-anilinothieno[2,3-b]pyridine-2-carboxamide | 3-azanyl-4-phenylazanyl-thieno[2,3-b]pyridine-2-carboxamide | MLS000061149 | SMR000069217 | cid_750059
Type:
Small organic molecule
Emp. Form.:
C14H12N4OS
Mol. Mass.:
284.336
SMILES:
NC(=O)c1sc2nccc(Nc3ccccc3)c2c1N
Structure:
Search PDB for entries with ligand similarity: