Reaction Details Report a problem with these data
Target
fMet-Leu-Phe receptor
Ligand
BDBM37758
Substrate
n/a
Meas. Tech.
Dose Response Assay for Formylpeptide Receptor (FPR) Ligands and Dose Response Counter-Screen Assay for Formylpeptide-Like-1 (FPRL1) Ligands
Ki
12700±n/a nM
Citation
 PubChem, PC Dose Response Assay for Formylpeptide Receptor (FPR) Ligands and Dose Response Counter-Screen Assay for Formylpeptide-Like-1 (FPRL1) Ligands PubChem Bioassay (2007)[AID] 
Target
Name:
fMet-Leu-Phe receptor
Synonyms:
FPR | FPR1 | FPR1_HUMAN | Formyl peptide Receptor | N-formyl peptide receptor 1 | N-formylpeptide chemoattractant receptor | fMLP receptor | fMet-Leu-Phe receptor | formyl peptide receptor 1
Type:
Enzyme Catalytic Domain
Mol. Mass.:
38456.14
Organism:
Homo sapiens (Human)
Description:
gi_4503779
Residue:
350
Sequence:
METNSSLPTNISGGTPAVSAGYLFLDIITYLVFAVTFVLGVLGNGLVIWVAGFRMTHTVTTISYLNLAVADFCFTSTLPFFMVRKAMGGHWPFGWFLCKFVFTIVDINLFGSVFLIALIALDRCVCVLHPVWTQNHRTVSLAKKVIIGPWVMALLLTLPVIIRVTTVPGKTGTVACTFNFSPWTNDPKERINVAVAMLTVRGIIRFIIGFSAPMSIVAVSYGLIATKIHKQGLIKSSRPLRVLSFVAAAFFLCWSPYQVVALIATVRIRELLQGMYKEIGIAVDVTSALAFFNSCLNPMLYVFMGQDFRERLIHALPASLERALTEDSTQTSDTATNSTLPSAEVELQAK
  
Inhibitor
Name:
BDBM37758
Synonyms:
2-furancarboxylic acid [3-(2-methoxyphenoxy)-2-methyl-4-oxo-1-benzopyran-7-yl] ester | 3-(2-methoxyphenoxy)-2-methyl-4-oxo-4H-chromen-7-yl 2-furoate | MLS000088046 | SMR000072255 | [3-(2-methoxyphenoxy)-2-methyl-4-oxidanylidene-chromen-7-yl] furan-2-carboxylate | [3-(2-methoxyphenoxy)-2-methyl-4-oxochromen-7-yl] furan-2-carboxylate | cid_1300651 | furan-2-carboxylic acid [4-keto-3-(2-methoxyphenoxy)-2-methyl-chromen-7-yl] ester
Type:
Small organic molecule
Emp. Form.:
C22H16O7
Mol. Mass.:
392.3582
SMILES:
COc1ccccc1Oc1c(C)oc2cc(OC(=O)c3ccco3)ccc2c1=O
Structure:
Search PDB for entries with ligand similarity: