Reaction Details Report a problem with these data
Target
fMet-Leu-Phe receptor
Ligand
BDBM37672
Substrate
n/a
Meas. Tech.
Dose Response Assay for Formylpeptide Receptor (FPR) Ligands and Dose Response Counter-Screen Assay for Formylpeptide-Like-1 (FPRL1) Ligands
IC50
>66700±n/a nM
Citation
 PubChem, PC Dose Response Assay for Formylpeptide Receptor (FPR) Ligands and Dose Response Counter-Screen Assay for Formylpeptide-Like-1 (FPRL1) Ligands PubChem Bioassay (2007)[AID] 
Target
Name:
fMet-Leu-Phe receptor
Synonyms:
FPR | FPR1 | FPR1_HUMAN | Formyl peptide Receptor | N-formyl peptide receptor 1 | N-formylpeptide chemoattractant receptor | fMLP receptor | fMet-Leu-Phe receptor | formyl peptide receptor 1
Type:
Enzyme Catalytic Domain
Mol. Mass.:
38456.14
Organism:
Homo sapiens (Human)
Description:
gi_4503779
Residue:
350
Sequence:
METNSSLPTNISGGTPAVSAGYLFLDIITYLVFAVTFVLGVLGNGLVIWVAGFRMTHTVTTISYLNLAVADFCFTSTLPFFMVRKAMGGHWPFGWFLCKFVFTIVDINLFGSVFLIALIALDRCVCVLHPVWTQNHRTVSLAKKVIIGPWVMALLLTLPVIIRVTTVPGKTGTVACTFNFSPWTNDPKERINVAVAMLTVRGIIRFIIGFSAPMSIVAVSYGLIATKIHKQGLIKSSRPLRVLSFVAAAFFLCWSPYQVVALIATVRIRELLQGMYKEIGIAVDVTSALAFFNSCLNPMLYVFMGQDFRERLIHALPASLERALTEDSTQTSDTATNSTLPSAEVELQAK
  
Inhibitor
Name:
BDBM37672
Synonyms:
3-(furan-2-carbonyl)-4-hydroxy-1-(5-methyl-1,2-oxazol-3-yl)-2-pyridin-3-yl-2H-pyrrol-5-one | 3-(furan-2-ylcarbonyl)-1-(5-methyl-1,2-oxazol-3-yl)-4-oxidanyl-2-pyridin-3-yl-2H-pyrrol-5-one | 3-[2-furanyl(oxo)methyl]-4-hydroxy-1-(5-methyl-3-isoxazolyl)-2-(3-pyridinyl)-2H-pyrrol-5-one | 4-(2-furoyl)-3-hydroxy-1-(5-methylisoxazol-3-yl)-5-(3-pyridyl)-3-pyrrolin-2-one | MLS000082280 | SMR000047093 | cid_665755
Type:
Small organic molecule
Emp. Form.:
C18H13N3O5
Mol. Mass.:
351.3129
SMILES:
Cc1cc(no1)N1C(C(C(=O)c2ccco2)C(=O)C1=O)c1cccnc1
Structure:
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