Reaction Details Report a problem with these data
Target
Free fatty acid receptor 4
Ligand
BDBM403683
Substrate
n/a
Meas. Tech.
GPR120 pERK AlphaScreen SureFire Assay
EC50
180±n/a nM
Citation
 Cheng, PT; Yoon, DS Phenyl-(aza)cycloalkyl carboxylic acid GPR120 modulators US Patent  US10336684 Publication Date 7/2/2019 
Target
Name:
Free fatty acid receptor 4
Synonyms:
FFAR4 | FFAR4_HUMAN | G-protein coupled receptor 120 | G-protein coupled receptor 129 | G-protein coupled receptor GT01 | G-protein coupled receptor PGR4 | GPR120 | GPR129 | O3FAR1 | Omega-3 fatty acid receptor 1 | PGR4
Type:
PROTEIN
Mol. Mass.:
42256.91
Organism:
Homo sapiens (Human)
Description:
ChEMBL_1508994
Residue:
377
Sequence:
MSPECARAAGDAPLRSLEQANRTRFPFFSDVKGDHRLVLAAVETTVLVLIFAVSLLGNVCALVLVARRRRRGATACLVLNLFCADLLFISAIPLVLAVRWTEAWLLGPVACHLLFYVMTLSGSVTILTLAAVSLERMVCIVHLQRGVRGPGRRARAVLLALIWGYSAVAALPLCVFFRVVPQRLPGADQEISICTLIWPTIPGEISWDVSFVTLNFLVPGLVIVISYSKILQTSEHLLDARAVVTHSEITKASRKRLTVSLAYSESHQIRVSQQDFRLFRTLFLLMVSFFIMWSPIIITILLILIQNFKQDLVIWPSLFFWVVAFTFANSALNPILYNMTLCRNEWKKIFCCFWFPEKGAILTDTSVKRNDLSIISG
  
Inhibitor
Name:
BDBM403683
Synonyms:
2-(4-((+/−)-3-Phenoxycyclohexyl)phenethoxy)acetic acid (racemic cis-1,3-cyclohexyl isomer; Absolute Stereochemistry is Arbitrarily Drawn) | US10336684, Example 4 | US10336684, Example 6
Type:
Small organic molecule
Emp. Form.:
C22H26O4
Mol. Mass.:
354.4394
SMILES:
OC(=O)COCCc1ccc(cc1)[C@@H]1CCC[C@@H](C1)Oc1ccccc1 |r|
Structure:
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